Elodie Modave
Katholieke Universiteit Leuven
15 Papers
19 Citations
Elodie Modave is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 5, co-authored 12 publications. Previous affiliations of Elodie Modave include University of Canberra & Flanders Institute for Biotechnology.
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Papers
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts.
Xing Yi Woo,Jessica Giordano,Anuj Srivastava,Zi-Ming Zhao,Michael Lloyd,Roebi de Bruijn,Yun-Suhk Suh,Rajesh Patidar,Li Chen,Sandra D. Scherer,Matthew H. Bailey,Chieh-Hsiang Yang,Emilio Cortes-Sanchez,Yuanxin Xi,Jing Wang,Jayamanna Wickramasinghe,Andrew V. Kossenkov,Vito W. Rebecca,Hua Sun,R. Jay Mashl,Sherri R. Davies,Ryan Jeon,Christian Frech,Jelena Randjelovic,Jacqueline Rosains,Francesco Galimi,Andrea Bertotti,Adam Lafferty,Alice C. O’Farrell,Elodie Modave,Diether Lambrechts,Petra ter Brugge,Violeta Serra,Elisabetta Marangoni,Rania El Botty,Hyun Soo Kim,Jong Il Kim,Han-Kwang Yang,Charles Lee,Dennis A. Dean,Brandi N. Davis-Dusenbery,Yvonne A. Evrard,James H. Doroshow,Alana L. Welm,Bryan E. Welm,Michael T. Lewis,Bingliang Fang,Jack A. Roth,Funda Meric-Bernstam,Meenhard Herlyn,Michael A. Davies,Li Ding,Shunqiang Li,Ramaswamy Govindan,Claudio Isella,Jeffrey A. Moscow,Livio Trusolino,Annette T. Byrne,Jos Jonkers,Carol J. Bult,Enzo Medico,Jeffrey H. Chuang +61 more
TL;DR: In this paper, the authors exhaustively analyzed copy number alterations in 1,451 PDX and matched patient tumor (PT) samples from 509 PDX models, and they showed strong CNA conservation from PTs through late-passage PDXs.
Single-cell transcriptome analysis of the Akimba mouse retina reveals cell-type-specific insights into the pathobiology of diabetic retinopathy
Inge Van Hove,Lies De Groef,Bram Boeckx,Elodie Modave,Tjing-Tjing Hu,Karen Beets,Isabelle Etienne,Tine Van Bergen,Diether Lambrechts,Lieve Moons,Jean H.M. Feyen,Michaël Porcu +11 more
TL;DR: This study identifies molecular pathways underlying inflammatory, metabolic and oxidative stress-mediated changes in the Akimba mouse model of diabetic retinopathy and distinguishes distinct functional subtypes of inflammatory and macroglial cells.
Experimental and computational modeling for signature and biomarker discovery of renal cell carcinoma progression.
Lindsay S. Cooley,Lindsay S. Cooley,Justine Rudewicz,Justine Rudewicz,Wilfried Souleyreau,Wilfried Souleyreau,Andrea Emanuelli,Andrea Emanuelli,Arturo Alvarez-Arenas,Arturo Alvarez-Arenas,Kim Clarke,Francesco Falciani,Maeva Dufies,Diether Lambrechts,Elodie Modave,Domitille Chalopin-Fillot,Raphael Pineau,Damien Ambrosetti,Jean-Christophe Bernhard,Alain Ravaud,Sylvie Negrier,Jean-Marc Ferrero,Gilles Pagès,Sebastien Benzekry,Sebastien Benzekry,Macha Nikolski,Andreas Bikfalvi,Andreas Bikfalvi +27 more
TL;DR: In this article, a combination of experimental and mathematical modeling was able to generate meaningful data for the prediction of the clinical evolution of Renal Cell Carcinoma (RCC) using large-scale transcriptome, genome and methylome analyses.
Dedicated macrophages organize and maintain the enteric nervous system
Maria Francesca Viola,Marta Chavero-Pieres,Elodie Modave,Marcello Delfini,Nathalie Stakenborg,Naomi Fabre,Iris Appeltans,Tobie Martens,Katy Vandereyken,H. Theobald,Jens Van Herck,Philippe Petry,Simon Verheijden,Sebastiaan De Schepper,Alejandro Sifrim,Zhaoyuan Liu,Florent Ginhoux,Mohamad Azhar,Andreas Schlitzer,Gianluca Matteoli,Katrin Kierdorf,Marco Prinz,G Van den Berghe,Thierry Voet,Guy E. Boeckxstaens +24 more
TL;DR: It is demonstrated that resident macrophages of the muscularis externa refine the ENS early in life by pruning synapses and phagocytosing enteric neurons, and later switch to a neuro-supportive function, indicating that the ENS is governed by a dedicated population of resident macrophages that adapts its phenotype and transcriptome to the timely needs of the ENS niche.
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Interleukin-6 is an activator of pituitary stem cells upon local damage, a competence quenched in the aging gland.
Annelies Vennekens,Emma Laporte,Florient Hermans,Florient Hermans,Benoit Cox,Elodie Modave,Elodie Modave,Adrian Janiszewski,Charlotte Nys,Hiroto Kobayashi,Hiroto Kobayashi,Bert Malengier-Devlies,Joel Chappell,Patrick Matthys,Marie-Isabelle Garcia,Vincent Pasque,Diether Lambrechts,Diether Lambrechts,Hugo Vankelecom +18 more
TL;DR: In this paper, single-cell RNA sequencing uncovered interleukin-6 (IL-6) as being upregulated upon damage, however only in young but not aging pituitary.
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