Yvonne C. Lee
Northwestern University
109 Papers
243 Citations
Yvonne C. Lee is an academic researcher from Northwestern University. The author has contributed to research in topics: Medicine & Rheumatoid arthritis. The author has an hindex of 28, co-authored 96 publications. Previous affiliations of Yvonne C. Lee include Maastricht University & Harvard University.
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Papers
Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis
Deepak A. Rao,Michael F. Gurish,Jennifer L. Marshall,Kamil Slowikowski,Chamith Y. Fonseka,Yanyan Liu,Laura T. Donlin,Lauren A. Henderson,Kevin Wei,Fumitaka Mizoguchi,Nikola Teslovich,Nikola Teslovich,Michael E. Weinblatt,Elena Massarotti,Jonathan S. Coblyn,Simon M. Helfgott,Yvonne C. Lee,Derrick J. Todd,Vivian P. Bykerk,Susan M. Goodman,Susan M. Goodman,Alessandra B. Pernis,Lionel B. Ivashkiv,Elizabeth W. Karlson,Peter A. Nigrovic,Peter A. Nigrovic,Andrew Filer,Christopher D. Buckley,James A. Lederer,Soumya Raychaudhuri,Michael B. Brenner +30 more
TL;DR: Using multidimensional cytometry, transcriptomics, and functional assays, a population of PD-1hiCXCR5− ‘peripheral helper’ T (TPH) cells that express factors enabling B-cell help, including IL-21, CXCL13, ICOS, and MAF are defined.
The role of the central nervous system in the generation and maintenance of chronic pain in rheumatoid arthritis, osteoarthritis and fibromyalgia
TL;DR: Data suggest that central pain-processing defects may alter the pain response in rheumatoid arthritis patients, and different classes of analgesics may be more effective than drugs that treat peripheral or nociceptive pain.
Chronic diseases in the European Union: the prevalence and health cost implications of chronic pain.
TL;DR: There does appear to be sufficient evidence to at least make addressing chronic pain a high priority alongside other chronic diseases as well as to conduct more research, particularly regarding cost.
278
Brain glial activation in fibromyalgia - A multi-site positron emission tomography investigation.
Daniel S. Albrecht,Anton Forsberg,Angelica Sandström,Angelica Sandström,Courtney Bergan,Diana Kadetoff,Diana Kadetoff,Ekaterina Protsenko,Jon Lampa,Yvonne C. Lee,Yvonne C. Lee,Caroline Olgart Höglund,Ciprian Catana,Simon Cervenka,Oluwaseun Akeju,Mats Lekander,Mats Lekander,Mats Lekander,George B. Cohen,Christer Halldin,Norman E. Taylor,Minhae Kim,Jacob M. Hooker,Robert R. Edwards,Vitaly Napadow,Vitaly Napadow,Eva Kosek,Eva Kosek,Marco L. Loggia +28 more
TL;DR: The first in vivo evidence supporting a role for glial activation in FM pathophysiology is provided, and higher subjective ratings of fatigue in FM patients were associated with higher [11C]PBR28 SUVR in the anterior and posterior middle cingulate cortices.
237
Pain persists in DAS28 rheumatoid arthritis remission but not in ACR/EULAR remission: a longitudinal observational study
Yvonne C. Lee,Jing Cui,Bing Lu,Michelle L. Frits,Christine Iannaccone,Nancy A. Shadick,Michael E. Weinblatt,Daniel H. Solomon +7 more
TL;DR: Among patients in DAS28 remission, patient global assessment, disability, fatigue, sleep problems, and self-efficacy are strongly associated withPain severity at baseline and 1 year, whereas inflammatory disease activity and joint damage are not significantly associated with elevated pain severity at either baseline or 1 year.