Yunyun Jiang
Baylor College of Medicine
11 Papers
51 Citations
Yunyun Jiang is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Intellectual disability & Biobank. The author has an hindex of 7, co-authored 11 publications. Previous affiliations of Yunyun Jiang include Human Genome Sequencing Center.
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Papers
SYT1-associated neurodevelopmental disorder: a case series
Kate Baker,Kate Baker,Sarah L. Gordon,Holly Melland,Fabian Bumbak,Daniel Scott,Daniel Scott,Tess J. Jiang,David J. Owen,Bradley J. Turner,Stewart Boyd,Mari Rossi,Mohammed Al-Raqad,Orly Elpeleg,Dawn Peck,Grazia M.S. Mancini,Martina Wilke,Marcella Zollino,Giuseppe Marangi,Heike Weigand,Ingo Borggraefe,Tobias B. Haack,Tobias B. Haack,Zornitza Stark,Simon Sadedin,Tiong Yang Tan,Yunyun Jiang,Richard A. Gibbs,Sara Ellingwood,Michelle D. Amaral,Whitley V. Kelley,Manju A. Kurian,Michael A. Cousin,F Lucy Raymond +33 more
TL;DR: The first international case series describing the neurodevelopmental disorder associated with Synaptotagmin 1 (SYT1) de novo missense mutations is presented, which features include movement abnormalities, severe intellectual disability, and hallmark EEG alterations.
Harmonizing Clinical Sequencing And Interpretation For The Emerge III Network
Hana Zouk,Eric Venner,Niall J. Lennon,Donna M. Muzny,Debra J. Abrams,Samuel E. Adunyah,Ladia Albertson-Junkans,Darren C. Ames,Paul S. Appelbaum,Samuel J. Aronson,Sharon Aufox,Lawrence J. Babb,Adithya Balasubramanian,Hana Bangash,Melissa A. Basford,Lisa Bastarache,Samantha Baxter,Meckenzie A. Behr,Barbara Benoit,Elizabeth J. Bhoj,Suzette J. Bielinski,Sarah T. Bland,Carrie L. Blout,Kenneth M. Borthwick,Erwin P. Bottinger,Mark Bowser,Harrison Brand,Murray H. Brilliant,Wendy Brodeur,Pedro J. Caraballo,David Carrell,Andrew Carroll,Berta Almoguera,Lisa M. Castillo,Victor Castro,Gauthami Chandanavelli,Theodore Chiang,Rex L. Chisholm,Kurt D. Christensen,Wendy K. Chung,Christopher G. Chute,Brittany City,Beth L. Cobb,John J. Connolly,Paul K. Crane,Katherine D. Crew,David R. Crosslin,Mariza de Andrade,Jessica De la Cruz,Shawn Denson,Josh C. Denny,Tim DeSmet,Ozan Dikilitas,Christopher A. Friedrich,Stephanie M. Fullerton,Birgit Funke,Stacey Gabriel,Vivian S. Gainer,Ali G. Gharavi,Andrew M. Glazer,Joseph T. Glessner,Jessica Goehringer,Adam S. Gordon,Chet Graham,Robert C. Green,Justin H. Gundelach,Jyoti G. Dayal,Heather S. Hain,Hakon Hakonarson,Maegan V. Harden,John B. Harley,Margaret Harr,Andrea L. Hartzler,M. Geoffrey Hayes,Scott J. Hebbring,Nora B. Henrikson,Andrew Hershey,Christin Hoell,Ingrid A. Holm,Kayla Marie Howell,George Hripcsak,Jianhong Hu,Gail P. Jarvik,Joy Jayaseelan,Yunyun Jiang,Yoonjung Yoonie Joo,Sheethal Jose,Navya Shilpa Josyula,Anne E. Justice,Sara E. Kalla,Divya Kalra,Elizabeth W. Karlson,Melissa A. Kelly,Brendan J. Keating,Eimear E. Kenny,Dustin Key,Krzysztof Kiryluk,Terrie Kitchner,Barbara J. Klanderman,Eric W. Klee,David C. Kochan,Viktoriya Korchina,Leah C. Kottyan,Christie Kovar,Emily Kudalkar,Iftikhar J. Kullo,Philip E. Lammers,Eric B. Larson,Matthew S. Lebo,Magalie S. Leduc,Ming Ta (Michael) Lee,Kathleen A. Leppig,Nancy D. Leslie,Rongling Li,Wayne H. Liang,Chiao-Feng Lin,Jodell E. Linder,Noralane M. Lindor,Todd Lingren,James G. Linneman,Cong Liu,Wen Liu,Xiuping Liu,John Lynch,Hayley Lyon,Alyssa Macbeth,Harshad Mahadeshwar,Lisa Mahanta,Brad Malin,Teri A. Manolio,Maddalena Marasa,Keith Marsolo,Michael J. Dinsmore,Sheila Dodge,Elizabeth Hynes,Phil Dunlea,Todd L. Edwards,Christine M. Eng,David Fasel,Alex Fedotov,QiPing Feng,Mark Fleharty,Andrea Foster,Robert R. Freimuth,Michelle L. McGowan,Elizabeth M. McNally,James Meldrim,Frank D. Mentch,Jonathan D. Mosley,Shubhabrata Mukherjee,Thomas E. Mullen,Jesse Muniz,David R. Murdock,Shawn N. Murphy,Mullai Murugan,Melanie F. Myers,Bahram Namjou,Yizhao Ni,Aniwaa Owusu Obeng,Robert C. Onofrio,Casey Overby Taylor,Thomas N. Person,Josh F. Peterson,Lynn Petukhova,Cassandra J. Pisieczko,Siddharth Pratap,Cynthia A. Prows,Megan J. Puckelwartz,Alanna Kulchak Rahm,Ritika Raj,James D. Ralston,Arvind Ramaprasan,Andrea H. Ramirez,Luke V. Rasmussen,Laura J. Rasmussen-Torvik,Hila Milo Rasouly,Soumya Raychaudhuri,Marylyn D. Ritchie,Catherine M. Rives,Beenish Riza,Dan M. Roden,Elisabeth A. Rosenthal,Avni Santani,Dan Schaid,Steven E. Scherer,Stuart A. Scott,Aaron Scrol,Soumitra Sengupta,Ning Shang,Himanshu Sharma,Richard R. Sharp,Rajbir Singh,Patrick M. A. Sleiman,Kara Slowik,Joshua C. Smith,Maureen E. Smith,Jordan W. Smoller,Sunghwan Sohn,Ian B. Stanaway,Justin Starren,Mary Stroud,Jessica Su,Kasia Tolwinski,Sara L. Van Driest,Sean M. Vargas,Matthew Varugheese,David L. Veenstra,Miguel Verbitsky,Gina Vicente,Michael Wagner,Kimberly Walker,Theresa L. Walunas,Liwen Wang,Qiaoyan Wang,Wei-Qi Wei,Scott T. Weiss,Georgia L. Wiesner,Quinn S. Wells,Chunhua Weng,Peter White,Ken Wiley,Janet L. Williams,Marc S. Williams,Michael W. Wilson,Leora Witkowski,Laura Allison Woods,Betty Woolf,Tsung-Jung Wu,Julia Wynn,Yaping Yang,Victoria Yi,Ge Zhang,Lan Zhang,Heidi L. Rehm,Richard A. Gibbs +234 more
TL;DR: This study accomplished integration of structured genomic results into multiple electronic health record (EHR) systems, setting the stage for clinical decision support to enable genomic medicine.
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The Return of Actionable Variants Empirical (RAVE) Study, a Mayo Clinic Genomic Medicine Implementation Study: Design and Initial Results.
Iftikhar J. Kullo,Janet E. Olson,Xiao Fan,Merin Jose,Maya S. Safarova,Carmen Radecki Breitkopf,Erin M. Winkler,David C. Kochan,Sara Snipes,Joel E. Pacyna,Meaghan Carney,Christopher G. Chute,Jyoti Gupta,Sheethal Jose,Eric Venner,Mullai Murugan,Yunyun Jiang,Magdi Zordok,Medhat Farwati,Maraisha Philogene,Erica Smith,Gabriel Q. Shaibi,Pedro J. Caraballo,Robert R. Freimuth,Noralane M. Lindor,Richard R. Sharp,Stephen N. Thibodeau +26 more
- 01 Nov 2018
TL;DR: Expected traits were present in 13% of participants with P/LP variants in non‐FH CVD genes, suggesting low penetrance; this estimate may change with additional testing performed as part of the clinical evaluation.
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Atlas-CNV: a validated approach to call single-exon CNVs in the eMERGESeq gene panel
Theodore Chiang,Xiuping Liu,Tsung-Jung Wu,Jianhong Hu,Fritz J. Sedlazeck,Simon D. M. White,Daniel J. Schaid,Mariza de Andrade,Gail P. Jarvik,David S. Crosslin,Ian B. Stanaway,David Carrell,John J. Connolly,Hakon Hakonarson,Emily E. Groopman,Ali G. Gharavi,Alexander Fedotov,Weimin Bi,Magalie S. Leduc,David R. Murdock,Yunyun Jiang,Linyan Meng,Linyan Meng,Christine M. Eng,Christine M. Eng,Shu Wen,Shu Wen,Yaping Yang,Yaping Yang,Donna M. Muzny,Eric Boerwinkle,Eric Boerwinkle,William J Salerno,Eric Venner,Richard A. Gibbs +34 more
TL;DR: Atlas-CNV is validated as a method to identify exonic CNVs in targeted sequencing data generated in the clinical laboratory and the ExonQC and C-score assignment can reduce FDR and improve calling accuracy of single-exon CNVs respectively.
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Xia-Gibbs syndrome in adulthood: a case report with insight into the natural history of the condition.
David R. Murdock,Yunyun Jiang,Michael F. Wangler,Michael M. Khayat,Aniko Sabo,Jane Juusola,Kirsty McWalter,Krista Sondergaard Schatz,Meral Gunay-Aygun,Richard A. Gibbs +9 more
- 03 Jun 2019
TL;DR: This individual is the oldest published XGS case to date, demonstrates the wide phenotypic spectrum of the disorder, and provides information on the condition's natural history.