10 Papers
17 Citations
Lu Yuan is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Cerebral blood flow & Stroke. The author has an hindex of 5, co-authored 10 publications.
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Papers
Induction and imaging of photothrombotic stroke in conscious and freely moving rats.
TL;DR: A rodent model of focal cerebral ischemia and real-time blood flow imaging opens the possibility of performing various fundamental and translational studies on stroke without the influence of anesthetics.
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Predicting the ischemic infarct volume at the first minute after occlusion in rodent stroke model by laser speckle imaging of cerebral blood flow
TL;DR: An on-line laser speckle imaging (LSI) system is implemented, which could provide real time high spatio-temporal resolution CBF information before, during, and immediately after the rat MCAO surgery, and finds a significant correlation between the affected area with 50% CBF reduction at the first minute after occlusion with the infarct volume.
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Hemodynamic effects of intraoperative anesthetics administration in photothrombotic stroke model: a study using laser speckle imaging
TL;DR: The results demonstrated that the hemodynamic features were affected by anesthetics at as early as during the stroke induction, and brought additional insights into understanding the translational difficulty in stroke research.
Intraoperative laser speckle contrast imaging improves the stability of rodent middle cerebral artery occlusion model
TL;DR: Using the real-time CBF50 marker to guide suture insertion during the surgery showed that intraoperative CBF-guided surgery could significantly improve the stability of MCAO with a more consistent infarct volume and less mortality.
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Single-trial estimation of the cerebral metabolic rate of oxygen with imaging photoplethysmography and laser speckle contrast imaging
TL;DR: iPPG and laser speckle contrast imaging were combined into a multi-modal optical imaging system for single-trial estimation of CMRO(2) and in a physiologically stable experiment, the iPPG-based method showed a less than 4% variance in comparison with the conventional method over 20 trials, and its temporal stability could be comparable to that byventional method over 6 trials.
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