13 Papers
23 Citations
Bin Bo is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Cerebral blood flow & Medicine. The author has an hindex of 3, co-authored 10 publications.
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Papers
Optogenetic translocation of protons out of penumbral neurons is protective in a rodent model of focal cerebral ischemia.
TL;DR: Results indicate that countering intracellular acidosis by optogenetically translocating protons out of penumbral neurons during the acute ischemic stage could induce protection after isChemic brain injury.
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Hemodynamic effects of intraoperative anesthetics administration in photothrombotic stroke model: a study using laser speckle imaging
TL;DR: The results demonstrated that the hemodynamic features were affected by anesthetics at as early as during the stroke induction, and brought additional insights into understanding the translational difficulty in stroke research.
Multifunctional Nanostructure RAP-RL Rescues Alzheimer's Cognitive Deficits through Remodeling the Neurovascular Unit.
Qian Zhang,Qingxiang Song,Xiao Gu,Mengna Zheng,Antian Wang,Gan Jiang,Meng Huang,Huan Chen,Yu Qiu,Bin Bo,Shanbao Tong,Rong Shao,Binyin Li,Gang Wang,Hao Wang,Yong-Bo Hu,Hong-Zhuan Chen,Hong-Zhuan Chen,Xiaoling Gao +18 more
TL;DR: The proof of concept that remodeling the functional NVU may represent a promising therapeutic approach toward effective intervention of AD is provided and the potential of the multifunctional nanostructure RAP‐RL as a disease‐modifying modality for AD treatment is demonstrated.
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An artificial‐intelligence‐based age‐specific template construction framework for brain structural analysis using magnetic resonance images
Dongdong Gu,Feng Shi,Rui Hua,Ying Wei,Yufei Li,Jiayu Zhu,Weijun Zhang,Han Zhang,Qiang Yang,Peiyu Huang,Yingling Jiang,Bin Bo,Yao Li,Yaoyu Zhang,Minming Zhang,Jinsong Wu,Hongcheng Shi,Siwei Liu,Qiang He,Qiang Zhang,Xu Zhang,Hongjiang Wei,Guocai Liu,Zhong Xue,Dinggang Shen +24 more
TL;DR: In this paper , an AI-based age-specific template construction (called ASTC) framework was proposed for longitudinal structural brain analysis using T1-weighted MRIs of 646 subjects from 18 to 82 years old collected from four medical centers.
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