Leiguo Ming
Fourth Military Medical University
11 Papers
34 Citations
Leiguo Ming is an academic researcher from Fourth Military Medical University. The author has contributed to research in topics: Mesenchymal stem cell & Regeneration (biology). The author has an hindex of 8, co-authored 9 publications.
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Papers
Advancing application of mesenchymal stem cell-based bone tissue regeneration
TL;DR: An overview of autogenous/allogenic and ECM-based bone biomaterials for reconstructive surgery and applications of MSCs-mediated bone healing and tissue engineering to further offer principles and effective strategies to optimize M SCs- based bone regeneration are discussed.
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Integration of a calcined bovine bone and BMSC-sheet 3D scaffold and the promotion of bone regeneration in large defects
TL;DR: Results of this study demonstrated that CBB-BMSC-sheet combination was a promising strategy in healing of large area bone defect in osteoporosis.
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The effect of licochalcone A on cell-aggregates ECM secretion and osteogenic differentiation during bone formation in metaphyseal defects in ovariectomized rats
TL;DR: Investigation of the feasibility of applying licochalcone-A (L-A) and bone marrow mesenchymal stem cells (BMSC)-aggregate in bone repairing tissue engineering and the biological effects of L-A on the cell aggregate formation and osteogenic properties found it to be a promising strategy in treating osteoporotic weight-bearing bones fractures with defects.
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Apocynin suppression of NADPH oxidase reverses the aging process in mesenchymal stem cells to promote osteogenesis and increase bone mass.
TL;DR: In this article, the expression of potential key targets influencing this reversal was evaluated using qRT-PCR, and the expression expression of p53 was shown to be reduced with the suppression of NOX.
Liver extracellular matrix promotes BM-MSCs hepatic differentiation and reversal of liver fibrosis through activation of integrin pathway.
TL;DR: Investigation of the hepatogenicity and underlying mechanism of L‐ECM as well as its potential regulative role in the MSC‐based liver recovery found it promotes hepatic differentiation of BM‐MSCs via the ITG pathway and plays a therapeutically beneficial role for stem cell-based liver regeneration.
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