Elke Maas
Katholieke Universiteit Leuven
7 Papers
53 Citations
Elke Maas is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Embryonic stem cell & Endothelium. The author has an hindex of 5, co-authored 7 publications.
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Papers
Stalk Cell Phenotype Depends on Integration of Notch and Smad1/5 Signaling Cascades
Iván M. Moya,Lieve Umans,Elke Maas,Paulo N. G. Pereira,Karen Beets,Annick Francis,Ward Sents,Elizabeth J. Robertson,Christine L. Mummery,Danny Huylebroeck,An Zwijsen +10 more
TL;DR: In vivo evidence is provided for a regulatory loop between BMP/TGFβ-Smad1/5 and Notch signaling that orchestrates tip- versus stalk-cell selection and vessel plasticity.
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Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in the mouse amnion
Paulo N. G. Pereira,Mariya P. Dobreva,Elke Maas,F.M. Cornelis,Iván M. Moya,Lieve Umans,Catherine M. Verfaillie,Anne Camus,Susana M. Chuva de Sousa Lopes,Danny Huylebroeck,An Zwijsen +10 more
TL;DR: It is concluded that antagonism of Nodal signaling by BMP/Smad5 signaling prevents primitive streak formation in the amnion of normal mouse embryos.
BMP-SMAD Signaling Regulates Lineage Priming, but Is Dispensable for Self-Renewal in Mouse Embryonic Stem Cells
Maria Gomes Fernandes,Ruben Dries,Ruben Dries,Matthias S Roost,Stefan Semrau,Ana de Melo Bernardo,Richard P. Davis,Ramprasad Ramakrishnan,Karoly Szuhai,Elke Maas,Lieve Umans,Lieve Umans,Lieve Umans,Vanesa Abon Escalona,Daniela C.F. Salvatori,Dieter Deforce,Wim Van Criekinge,Danny Huylebroeck,Danny Huylebroeck,Christine L. Mummery,An Zwijsen,Susana M. Chuva de Sousa Lopes,Susana M. Chuva de Sousa Lopes +22 more
TL;DR: It is shown that BMP-SMAD signaling modulates lineage priming in mESCs, by transiently regulating the enzymatic machinery responsible for DNA methylation, which is dispensable for self-renewal in both naive and ground state.
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BMP-SMAD signalling output is highly regionalized in cardiovascular and lymphatic endothelial networks.
Karen Beets,Michael W. Staring,Nathan Criem,Elke Maas,Niels Schellinx,Susana M. Chuva de Sousa Lopes,Lieve Umans,An Zwijsen +7 more
TL;DR: The data reveals the highly dynamic nature of BMP-SMAD mediated transcriptional regulation in time and space throughout the vascular tree, supporting that BMP -SMAD signalling can be a source of phenotypic diversity in some, but not all, healthy endothelium.
Multifaceted actions of Zeb2 in postnatal neurogenesis from the ventricular-subventricular zone to the olfactory bulb
Astrid Deryckere,Elke Stappers,Elke Stappers,Ruben Dries,Ruben Dries,Elise Peyre,Veronique van den Berghe,Veronique van den Berghe,Andrea Conidi,F. Isabella Zampeta,Annick Francis,Marjolein Bresseleers,Agata Stryjewska,Ria Vanlaer,Elke Maas,Ihor Smal,Wilfred F. J. van IJcken,Frank Grosveld,Laurent Nguyen,Danny Huylebroeck,Danny Huylebroeck,Eve Seuntjens,Eve Seuntjens +22 more
TL;DR: The transcription factor Zeb2 uses distinct molecular subdomains to regulate olfactory bulb interneuron generation and maturation from the young postnatal ventricular-subventricular zone in mice, suggesting that Zeb 2 partners co-determine neuronal output from the mouse V-SVZ in both quantitative and qualitative ways in early postnatal life.
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