David M. Systrom
Brigham and Women's Hospital
146 Papers
834 Citations
David M. Systrom is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Medicine & Pulmonary hypertension. The author has an hindex of 37, co-authored 120 publications. Previous affiliations of David M. Systrom include Boston Children's Hospital & National Institutes of Health.
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Papers
Sildenafil Improves Exercise Capacity and Quality of Life in Patients with Systolic Heart Failure and Secondary Pulmonary Hypertension
Gregory D. Lewis,Ravi V. Shah,Khurram Shahzad,Janice M. Camuso,Paul P. Pappagianopoulos,Judy Hung,Ahmed Tawakol,Robert E. Gerszten,David M. Systrom,Kenneth D. Bloch,Marc J. Semigran +10 more
TL;DR: In this article, the authors tested the hypothesis that sildenafil, an effective therapy for pulmonary arterial hypertension, would lower pulmonary vascular resistance and improve exercise capacity in patients with systolic heart failure complicated by secondary pulmonary hypertension.
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Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection.
Tanayott Thaweethai,Sarah E. Jolley,Elizabeth W. Karlson,Emily B. Levitan,Bruce D. Levy,Grace A. McComsey,Lisa McCorkell,Girish N. Nadkarni,Sairam Parthasarathy,Upinder Singh,Tiffany A Walker,Caitlin A. Selvaggi,Daniel J Shinnick,Carolin C.M. Schulte,Leora I. Horwitz,Andrea S. Foulkes,Judith A. Aberg,Natalie L. Adolphi,Shreya Ahirwar,Neera Ahuja,Aseel Al-Jadiri,N. S. Alekhina,Heather Algren,Akram N. Alshawabkeh,A. Anand,Brett R. Anderson,Lisa Aponte-Soto,Andrew M. Atz,Robin L. Aupperle,Eduardo Azziz-Baumgartner,L. Conner Bailey,Fiona C. Baker,Venkataraman Balaraman,Jennifer A. Bandy,Dithi Banerjee,Deanna M. Barch,James M. Bardes,R. Graham Barr,Arielle R. Baskin-Sommers,S. K. Basu,Tracy A. Battaglia,Carmen Beamon,Noam D. Beckmann,Jasmine A. Berry,Nahid Bhadelia,Daksh Bhargava,S. A. Bhuiyan,Jiang Bian,Christian Bime,James M. Bjork,Lora Jane Black,Catherine A. Blish,Jason P. Block,Amanda Bogie,Dawn Bolliger,Seuli Bose-Brill,Mary Bower,Andrew D. Bond,Jerusha Boyineni,Steven B. Bradfute,Carolyn T. Bramante,Molly Brannock,J. Douglas Bremner,Shari B. Brosnahan,Elliott Bueler,Irina A. Buhimschi,Hulya Bukulmez,H. Timothy Bunnell,John B. Buse,Elizabeth A. Calhoun,Tingyi Cao,Michael D. Carrithers,Thomas W Carton,Abigail Case,B. Casey,Faye Victoria C. Casimero,Lauren Castro,Patricia Ceger,Connie L Cerullo,A. Chang,Praneeth Chebrolu,Yong Chen,Li Qing Chen,Benjamin K. Chen,David Chestek,Robert F Chew,Deena J. Chisolm,Dominic C. Chow,Maryanne R.K. Chrisant,Dimitri A. Christakis,Christopher G. Chute,Mine S. Cicek,Cheryl R Clark,Duncan B. Clark,Geoffrey D. Clarke,Katharine N. Clouser,Thomas J. Connors,Judith A. Cook,Carlos Cordon-Cardo,Lesley Cottrell,Kelly J. Cowan,Lindsay G. Cowell,S. K. Cranford,Mollie R. Cummins,Hannah Curry,Viren D'Sa,Casey L. Daniel,Mirella Dapretto,Dawood Darbar,Paul M. Darden,Raktima Dasgupta,Soham Dasgupta,Katherine Dea,Sara J. Deakyne Davies,Lauren A. Decker,Ralph A. DeFronzo,Walter Dehority,Amelia N. Deitchman,Phoebe Del Boccio,Carlos del Rio,Marina Del Rios,Julie A. DeLisa,Sean Deoni,John D. Dickinson,Audrey Dionne,Kathleen R. Diviak,Sarah E. Donohue,M. J. Downey,Allen J. Dozor,Benard P. Dreyer,Kirsten Dummer,Matthew S Durstenfeld,Mark S. Dworkin,Matthew D. Elias,Jamie Elifritz,Angela M. Ellison,Michael D. Evans,Julio C. Facelli,Edward Vincent S. Faustino,Candace H. Feldman,Alexander G. Fiks,Rebecca Fineman,Aloke V. Finn,Megan Fitzgerald,Valerie J. Flaherman,Thomas J. Flotte,Daniel Forsha,Meghan R. Fortune,John J. Foxe,Nicole Franks,Michael B. Freedman,Naomi Friedman,G.P. Fry,Margot Gage Witvliet,Emily R. Gallagher,R Gallagher,Hugh Garavan,Sunanda Gaur,Dylan G. Gee,Maria Laura Gennaro,Lynn B. Gerald,Saikat Ghosh,Joseph T. Giacino,Andrew T. Girvin,Mark P. Goldberg,Steven N. Goodman,Howard S. Gordon,Ramkiran Gouripeddi,Paige K. Graham,J.P. Granger,Kevin M. Gray,Rachel S. Gross,Emily Hadley,Melissa A. Haendel,Stephanie I. Hafner,Katia C Halabi,Patrick Hanley,Ashraf S Harahsheh,Michelle Harkins,Keren Hasbani,Kristine Hauser,Andrew C. Heath,Camden Hebson,Mary M. Heitzeg,Monica Hendrickson,Timothy J. Henrich,Alfonso C Hernandez-Romieu,Christina M. Hester,S. Hill,Kathryn Hirabayashi,On Ho,Laura J. Hobart-Porter,Micah C. Hoffman,Maryann Holtcamp,Travis Hong,Benjamin D. Horne,Carol R. Horowitz,Daniel Hsia,Priscilla Y. Hsue,Matthew J. Huentelman,Jared D. Huling,William G. Iacono,C.U Ibeawuchi,Katherine Irby,Nahed Ismail,Jan Jacobus,Vanessa L. Jacoby,Leonard A. Jason,Vidhi Javia,Kyle J. Jennette,Terry L. Jernigan,Sihang Jiang,Naimin Jing,Jace D Johnny,Nadia I. Johnson,Brandi T. Johnson,Brandon Johnson,Pei-Ni Jone,Suzanne E. Judd,Joy J Juskowich,Edmond K. Kabagambe,David C. Kaelber,Diane G. Kanjilal,Mayank Kansal,Daniel Kaufman,Rika Kawakami,Dean L. Kellogg,Denise A. Kent,Deepshikha Kewlani,Dhruv Khullar,Keri Kim,Arthur Y. Kim,Patricia A. Kinser,Lawrence C. Kleinman,Elizabeth B. Klerman,Matthew Kluko,Stacey Knight,Masaaki Kobayashi,Karla J. Kopp,Michael Koropsak,Jessica S. Kosut,Ellen Kraig,Amanda J. Krausert,Ana C. Krieger,Hema Krishna,A. Krishnamoorthy,Sankar Krishnan,Angela Laird,Victoria Laleau,Michelle F. Lamendola-Essel,Jeremy Landeo-Gutierrez,Christine L. Larson,James P. Lash,Jessica Lasky-Su,Gregory Laynor,Simon Lee,G. Lee,F. E. Lee,Matthew A. Lee,Peter Leese,Ryan Lefebvre,Ken Lewis,Lucia Li,Janet Lin,Krista M. Lisdahl,Matthew B Litvack,J. Lloyd,Jennifer Logue,Johanna Loomba,Vitaly Lorman,Katelyn R. Ludwig,Allison Lutz,Abeer M. Mahmoud,Cheryl L. Maier,Shahdi Malakooti,S. N. Malchenko,Gail Mallett,Gabrielle Maranga,Megan W. Martel,Susanne P. Martin-Herz,Maria Martinez-Lage,Christine Maughan,Cammeo Mauntel-Medici,Heidi T May,Kenneth H. Mayer,Diego R. Mazzotti,Caitryn M. McCallum,Brian W. McCrindle,Russell J. McCulloh,Dylan McDonald,Stephanie M. McInnis,Julie A. McMurry,Asuncion Mejias,Jonathan Melamed,Martha Menchaca,Alan L. Mendelsohn,Lucio Miele,Mitchell G. Miglis,Cris Milne,Joshua D. Milner,Roger A Mitchell,Murray A. Mittleman,Sindhu Mohandas,Lerraughn M. Morgan,D. Morozyuk,Keith E. Morse,Erick Moyneur,Praveen C. Mudumbi,Eva M. Müller-Oehring,Naoko Muramatsu,H. Brad Musick,Kshema Nagavedu,Erica R. Nahin,Anoop M. Nambiar,Benjamin H. Natelson,Michael C. Neale,Manette Ness-Cochinwala,Jane W. Newburger,Lauren R. Nichols,Sheila M. Nolan,Seth Noland,Richard M. Nowak,George T. O'Connor,John J. O'Keefe,Princess U. Ogbogu,C. R. Oliveira,Matthew E. Oster,Robert F. Padera,Henry Paik,Nathan M. Pajor,Huaqin Pan,Deepti Pant,and Lynda J. Partridge,Payal Patel,S. Patel,Khushboo Patel,Martin P. Paulus,Ann Pearman,Myriam Peralta-Carcelen,Emily R. Pfaff,De-Ann M. Pillers,Chloe E. Pitsch,Neil H. Pliskin,Michael A. Portman,Radu Postelnicu,Jennifer Sharpe Potter,Bellur S. Prabhakar,Priya Prahalad,Bharati Prasad,Alexander J. Preiss,Heather M. Prendergast,Davin K. Quinn,Yuri Quintana,Dustin J. Rabideau,Jonathan Radosta,Hengameh H. Raissy,Ramaswamy Ramchandran,S. Rao,Amy Rapkiewicz,Sonja Rasmussen,Hanieh Razzaghi,Candida J. Rebello,Paulina A. Rebolledo,N. Venkataramana Reddy,Cara Reedy,Jalees Rehman,Robert Ross Reichard,Kyung E. Rhee,M. Rice,John Rizzo,Nadia R. Roan,Polly Robarts,Timothy T. Roberts,Kathy Rodgers,C. M. Rogerson,M. E. Romero,Johana M. Rosas,Erika B. Rosenzweig,Russel L Rothman,Nadine Rouphael,Mark W. Russell,Arash Alen Sabati,Samer Sader,Marzieh Salehi,Amy L. Salisbury,Barbara A. Sampson,Yamuna Sanil,Alice I. Sato,Sharon Saydah,Michael S. Schechter,Edward J. Schenck,Julia Schuchard,Jennifer A Sculley,Alan C. Seifert,Rangaraj Selvarangan,Sudha Seshadri,Howard D. Sesso,Dimpy Shah,Divya Shakti,Nancy L. Shapiro,Suchetha Sharma,Kumar Sharma,Shubhi Sharma,Kavita Sharma,Gwendolyn DuBois DuBois Shaw,Eyal Shemesh,Yishan Shen,Elia M. Shenkman,Stephanie Shiau,M F R A Mazzeo and Siciliano,Aylin Simsir,Jessica Snowden,Isaac H. Solomon,Leslie Spikes,Lindsay M. Squeglia,Shubhika Srivastava,Kenneth A. Stapleford,Cheryl R Stein,Michelle D. Stevenson,Sarah A Stewart de Ramirez,Lauren E. Stiles,Aryeh Stock,Melissa S. Stockwell,James R. Stone,Jeran K. Stratford,Til Stürmer,Vignesh Subbian,Jun Sun,Mehul S. Suthar,Ashley Sylvera,David M. Systrom,Jacqueline R. Szmuszkovicz,Maria Talavera-Barber,Kelan G. Tantisira,Ronald J. Teufel,Deepika Thacker,Mansi R. Thakrar,Stephen N. Thibodeau,Moriah E. Thomason,Jiayi Tong,R. T. Torres,Jessica Traenkner,Robin Tragus,Joel D. Trinity,Jena Shaw Tronieri,Andrea B. Troxel,Jennifer Truong,Dongngan T. Truong,Joel Tsevat,Paul J. Utz,Viola Vaccarino,Terry L. Vanden Hoek,Nita Vangeepuram,Jay K. Varma,Suzanne D. Vernon,Adam S. Vohra,Laura Wagner,Fei Wang,David A. Warburton,Rebecca L Watkins,Sara E. Watson,Ryan Webb,Mark G. Weiner,Alan Werzberger,Jennifer Wheeler,Kenneth J. Wilkins,Natasha Jane Williams,Charley Williams,Scott C. Woller,R. Wong,Jeremy P. Wood,John C. Wood,Yinglin Xia,Jie Xu,Samuel Yang,H. Shonna Yin,Hsiang-Shu Yin,Yung Jae Yoo,Natalie Young,Chengxi Zang,William T. Zempsky,Yongkang Zhang,Emily Zimmerman,George A. Alba,Radica Z. Alicic,Natasha Altman,K. Anglin,Urania Argueta,Hassan Ashktorab,Gaston Baslet,Ingrid V. Bassett,Lucinda Bateman,Brahmchetna Bedi,Shamik Bhattacharyya,Marie-Abele Bind,Andra L. Blomkalns,Hector Bonilla,Patricia A. Bush,Mario Castro,James Chan,Alexander W. Charney,Peter Chen,Lori B Chibnik,Helen Y. Chu,Rebecca G. Clifton,Maged M. Costantine,Sushma K. Cribbs,Steven G. Deeks,Ivette F. Emery,Nathaniel B. Erdmann,Kristine M. Erlandson,Kacey C. Ernst,Rachael M Farah-Abraham,Cheryl Farner,Elen M Feuerriegel,J. Fleurimont,Vivian Fonseca,Nicholas Franko,Vivian S. Gainer,Jennifer C. Gander,Edward M. Gardner,Linda Geng,Kelly S. Gibson,Minjoung Go,Jason D Goldman,Frank L. Greenway,Mounira Habli,John H. Hafner,Jenny E. Han,Keith Hanson,James R. Heath,Rachel Hess,Sally Hodder,Matthew Hoffman,Susan E. Hoover,Beatrice Huang,Brenna L. Hughes,Prasanna Jagannathan,Janice N. John,Michael I. Jordan,Stuart D. Katz,Elizabeth S. Kaufman,John J. Kelly,Sara Kelly,Megan M Kemp,John P. Kirwan,Jonathan D. Klein,K. Knox,Jerry A. Krishnan,Andre Kumar,Adeyinka O. Laiyemo,Allison Lambert,Margaret Lanca,Joyce K. Lee-Iannotti,Michele Longo,Carlos A. Luciano,Karen Lutrick,Jason H. Maley,Jai G Marathe,Vincent C. Marconi,Gailen D. Marshall,Christopher F. Martin,Yuri Matusov,Alem Mehari,Hector Mendez-Figueroa,Robin J. Mermelstein,Torri D. Metz,Richard P. Morse,Jarrod Mosier,C. Mouchati,Janet Mullington,Shawn N. Murphy,Robert B. Neuman,Janko Ž Nikolich,Ighovwerha Ofotokun,Anna Palatnik,Kristy Palomares,Tanyalak Parimon,Samuel Parry,Jan E. Patterson,Thomas L. Patterson,Rachel E. Patzer,Michael J. Peluso,Priscilla Pemu,Christian M. Pettker,Beth A. Plunkett,Kristen Pogreba-Brown,Athena Poppas,John G. Quigley,Uma Maheswara Reddy,Rebecca Reece,H. T. Reeder,W. Brian Reeves,Eric M. Reiman,Franz Rischard,Jonathan Rosand,Dwight J. Rouse,Adam Michael Ruff,George A. Saade,Grecio Sandoval,Shannon M. Schlater,Fitzgerald Shepherd,Zaki A. Sherif,Hyagriv N. Simhan,Nora G. Singer,Daniel W. Skupski,A. Sowles,Jeffrey A. Sparks,Fatima Imran Sukhera,Barbara S. Taylor,Larissa Teunis,Robert Thomas,John M. Thorp,Paul J. Thuluvath,Alan T.N. Tita,Katherine R. Tuttle,Alfredo E. Urdaneta,Daisy Valdivieso,Timothy M. VanWagoner,A. J. Vasey,Monica Verduzco-Gutierrez,Zachary S. Wallace,Honorine D. Ward,David E. Warren,Steven J. Weiner,S. Welch,Sidney W. Whiteheart,Zanthia Wiley,Juan P. Wisnivesky,Lynn M. Yee,Sokratis N Zisis +630 more
TL;DR: This article developed a definition of postacute sequelae of SARS-CoV-2 infection (PASC) using self-reported symptoms and described PASC frequencies across cohorts, vaccination status, and number of infections.
Dynamic regulation of circulating microRNA during acute exhaustive exercise and sustained aerobic exercise training
Aaron L. Baggish,Andrew E. Hale,Rory B. Weiner,Gregory D. Lewis,David M. Systrom,Francis Wang,Thomas J. Wang,Stephen Y. Chan +7 more
TL;DR: In this paper, a longitudinal, repeated measures study was conducted to determine whether c-miRNAs are dynamically regulated in response to acute exhaustive cycling exercise and sustained rowing exercise training.
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Metabolic Signatures of Exercise in Human Plasma
Gregory D. Lewis,Laurie A. Farrell,Malissa J. Wood,Maryann E. Martinovic,Zoltan Arany,Glenn C. Rowe,Amanda Souza,Susan Cheng,Susan Cheng,Elizabeth L. McCabe,Elaine Yang,Xu Shi,Rahul C. Deo,Frederick P. Roth,Aarti Asnani,Eugene P. Rhee,Eugene P. Rhee,David M. Systrom,Marc J. Semigran,Ramachandran S. Vasan,Steven A. Carr,Thomas J. Wang,Marc S. Sabatine,Marc S. Sabatine,Clary B. Clish,Robert E. Gerszten +25 more
TL;DR: Plasma metabolic profiles obtained during exercise provide signatures of exercise performance and cardiovascular disease susceptibility, in addition to highlighting molecular pathways that may modulate the salutary effects of exercise.
Cardiopulmonary Exercise Testing: What Is its Value?
TL;DR: This review highlights modern CPET use as a single or combined test that allows the pathophysiological bases of exercise limitation to be translated, quite easily, into clinical practice.
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