Michael D. Carrithers

TL;DR: It is demonstrated that CD31-deficient mice have reduced survival during endotoxic LPS-induced shock and suggested thatCD31 is necessary for maintenance of endothelial integrity and prevention of apoptosis during septic shock and for STAT3-mediated acute phase responses that promote survival during sepsis.

TL;DR: It is asked whether a protective effect would persist after withdrawal of a sodium channel blocker in patients with multiple sclerosis.

TL;DR: It is hypothesize that genetically determined kinetics of immune surveillance may regulate the phenotype of subsequent CNS inflammation by facilitating early CNS migration of a CD4 Th1 cell line.

TL;DR: Peptide dimers can be synthesized easily and have enhanced functional activity; monospecific dimers have greater avidity and bispecificDimers are likely to have greater selectivity and have practical potential as specific cell-targeting agents.