Toothpaste

Abstract: Many different kind of ingredients are incorporated in toothpastes and mouthwashes to keep the oral health in a perfect condition. We have different kinds of toothpastes and mouthwashes available in the market like anti-cavity, extra-whitening and toothpaste for sensitive teeth, toothpastes with stripes, clear and even liver flavored toothpaste for dogs. Modern type of toothpaste contains abrasives which help to scour off bacterial films and fluorides to harden the teeth against caries and have thickeners that stay on the toothbrush. The role of detergents is to remove the fatty films, and water softeners to make the detergents work better. The sweeteners play the role as a non-nutritive which may help stop the attraction of bacteria. Different kind of ingredients incorporate such as detergents and phosphates to prevent the awful taste. A variety of mouthwashes are available in the market according to the different oral conditions like antibacterial mouthwash, whiting mouthwash, fluoride mouthwash and bad breath mouthwash which have a strong enough flavor to hide the bad tastes of decaying bits of previous meals. Both mouthwashes and toothpastes contain active and inactive ingredients which have their own importance and will be recommended according to their different oral conditions. : Toothpastes, Mouthwashes, Fluoride,Abrasive, Potassium nitrate, Chlorhexidine

Abstract: The purpose of this three-month, double-blind, parallel-design clinical study was to compare the efficacy of two commercially available dentifrices, Herbal Toothpaste and Gum Therapy and Colgate Total, in controlling gingivitis, gingival bleeding, plaque and stain. Forty healthy adult volunteers from the Junior Comprehensive Care Clinics at New York University College of Dentistry were accepted as subjects for this clinical trial. To be eligible for a baseline clinical examination, subjects had to first indicate that during the previous six months they habitually brushed their teeth two or more times per day, and had noticed "bleeding gums" or "blood in the toothpaste" after brushing or flossing their teeth. At the baseline examination, subjects were enrolled in the study if they had at least five Loe-Silness gingival bleeding sites and 20 natural teeth, including all anterior teeth and four molars. An independent t-test before treatment indicated that there were no significant differences between the two groups at baseline. A one-way Analysis of Variance indicated that both dentifrices had a significant effect on gingivitis, gingival bleeding, plaque, and dental stain (p < 0.05). No significant statistical differences were observed between Herbal Toothpaste and Gum Therapy and Colgate Total for gingivitis or gingival bleeding. Herbal Toothpaste and Gum Therapy produced statistically significant differences in reducing plaque and stain relative to Colgate Total (p < 0.05). The results obtained in this study support the clinical efficacy of both products in reducing gingivitis and plaque, and demonstrate the efficacy of Herbal Toothpaste and Gum Therapy in maintaining reductions of plaque and stain.

Abstract: Pharmaceutical composition of skin respiratory factor (SRF), sodium chloride, bicarbonate, fluoride and zinc chloride in a suitable toothpaste vehicle provides effective therapy for gingivitis when brushed on the teeth and gingivae. Pharmaceutical composition of SRF in a viscous composition suitable for application to the gingivae and effective over an extended period of time for healing tissue damaged by gingevitis. A toothpaste tube for packaging a pharmaceutical composition of SRF, sodium chloride, bicarbonate, fluoride and zinc chloride.

Abstract: This study evaluated the effect of a CPP-containing toothpaste and compared it with fluoride-containing toothpastes on remineralization of caries-like lesions in primary teeth enamel, using polarized light microscopy. Forty-eight sound primary incisors were coated with nail varnish, leaving two 1x1 mm win- dows before being placed in a demineralizing solution for 4 days. After demin- eralization, all the specimens were coated with nail varnish over one window and were randomly assigned to 4 groups (A to D; n = 12). Group A teeth were exposed to distilled water. Group B teeth were exposed to a CPP-containing tooth- paste (Hi Herb ® ). Group C teeth were exposed to a 260 ppm fluoride-containing toothpaste (Smile baby toothgel ® ). Group D teeth were exposed to a 500 ppm fluoride-containing toothpaste (Oralmed ® Kid). Polarized light microscopy was used to evaluate lesion depth, before and after a 7-day pH cycle. Lesion depth was measured using a computerized method with the Image-Pro ® Plus program. Differences in mean lesion depth within groups and between groups were ana- lysed using the paired t-test, Kruskal-Wallis test and Mann-Whitney U test at a 95% level of confidence. Mean lesion depths in Groups A, B, C and D significantly increased by 110.1, 36.1, 40.2 and 18.2%, respectively. The mean lesion depths for all the toothpaste groups (B, C and D) were significantly different from the control group (A). Comparisons made among treatment groups showed Group D was significantly different from Groups B and C. All toothpastes were effective for inhibiting progression of carious lesions. However, a 500 ppm fluoride-containing toothpaste inhibited lesion progression better than a CPP-containing toothpaste and a 260 ppm fluoride-containing toothpaste.