Topic
Mitral valve repair
About: Mitral valve repair is a research topic. Over the lifetime, 5487 publications have been published within this topic receiving 107726 citations.
Papers published on a yearly basis
1 / 2
Papers
2,304 citations
TL;DR: New valve surgery models using contemporary data that include both valve repair as well as replacement are developed, expanding upon existing valve models, and include several nonfatal complications in addition to mortality.
1,270 citations
TL;DR: The effectiveness and durability of the central double-orifice technique were assessed and it was found that this type of repair can be a useful addition to the surgical armamentarium in mitral valve reconstruction.
980 citations
TL;DR: Percutaneous repair with the MitraClip system can be accomplished with low rates of morbidity and mortality and with acute MR reduction to < 2+ in the majority of patients, and with sustained freedom from death, surgery, or recurrent MR in a substantial proportion.
959 citations
University of Pennsylvania1, Icahn School of Medicine at Mount Sinai2, Université de Montréal3, Laval University4, Duke University5, Harvard University6, Cleveland Clinic7, Emory University8, Columbia University9, University of Maryland, Baltimore10, Baylor University Medical Center11, East Carolina University12, National Institutes of Health13, Yeshiva University14, University of Virginia15, Christiana Care Health System16
TL;DR: Replacement provided a more durable correction of mitral regurgitation, but there was no significant between-group difference in clinical outcomes.
Abstract: Background Ischemic mitral regurgitation is associated with a substantial risk of death. Practice guidelines recommend surgery for patients with a severe form of this condition but acknowledge that the supporting evidence for repair or replacement is limited. Methods We randomly assigned 251 patients with severe ischemic mitral regurgitation to undergo either mitral-valve repair or chordal-sparing replacement in order to evaluate efficacy and safety. The primary end point was the left ventricular end-systolic volume index (LVESVI) at 12 months, as assessed with the use of a Wilcoxon rank-sum test in which deaths were categorized below the lowest LVESVI rank. Results At 12 months, the mean LVESVI among surviving patients was 54.6±25.0 ml per square meter of body-surface area in the repair group and 60.7±31.5 ml per square meter in the replacement group (mean change from baseline, −6.6 and −6.8 ml per square meter, respectively). The rate of death was 14.3% in the repair group and 17.6% in the replacement g...
891 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2026 | 1 |
| 2025 | 94 |
| 2024 | 145 |
| 2023 | 179 |
| 2022 | 357 |
| 2021 | 376 |