Topic
Liver Leiomyosarcoma
About: Liver Leiomyosarcoma is a research topic. Over the lifetime, 6 publications have been published within this topic receiving 66 citations.
Papers
TL;DR: In this article, the computed tomographic findings of two cases of primary location in the liver were reported, and the differential diagnosis of such lesions were discussed, as well as the diagnosis of primary hepatic leiomyosarcomas.
Abstract: Primary hepatic leiomyosarcomas are exceedingly rare tumors. To the best of our knowledge, only 17 cases have been reported in literature. We report the computed tomographic findings of two cases of primary location in the liver. We also discuss the differential diagnosis of such lesions.
42 citations
TL;DR: Both autopsy cases of leiomyosarcoma of the liver in a 49‐year old female and 63‐year‐old male, showed extensive distant metastases in spite of an evident difference in their mitotic indices, indicating that this index is not reliable for judging the metastatic potential of these tumors.
Abstract: Two autopsy cases of leiomyosarcoma of the liver in a 49-year old female and 63-year-old male are reported. Both of the liver tumors showed electron microscopically dense patches in the cytoplasm and intermediate junctions between the tumor cells, suggesting a smooth muscle cell origin, irrespective of their different histological features. The nature of both tumors was confirmed by positive immunoreactivity for muscle-specific actin in the tumor cells, whereas desmin immunoreactivity was labile in both cases, showing a higher diagnostic value of the former compared with the latter in these leiomyosarcomas. Both cases, showed extensive distant metastases in spite of an evident difference in their mitotic indices, indicating that this index is not reliable for judging the metastatic potential of these tumors. Acta Pathol Jpn 41: 461–465, 1991.
15 citations
TL;DR: This case is an extremely rare case of malignant transformation from primary STUMP to metastatic hepatic leiomyosarcoma and provides important evidence regarding the treatment for metastatic cirrhosis of the liver associated with STUMP.
Abstract: Metastatic hepatic leiomyosarcoma is a rare malignant smooth muscle tumor. We report a case of metastatic hepatic leiomyosarcoma associated with smooth muscle tumor of uncertain malignant potential (STUMP). A 68-year-old female presented with a liver mass (60 mm × 40 mm, Segment 4). She underwent left salpingo-oophorectomy for an ovary tumor with STUMP in a broad ligament 6 years ago. Though FDG-PET showed obvious metabolically active foci, abnormal metabolically active foci other than the lesion were not detected. A malignant liver tumor was strongly suspected and laparoscopic partial liver resection was performed with vessel-sealing devices using the crush clamping method and Pringle maneuver. Immunohistochemical findings revealed metastatic liver leiomyosarcoma associated with STUMP in a broad ligament. This case is an extremely rare case of malignant transformation from primary STUMP to metastatic hepatic leiomyosarcoma. It provides important evidence regarding the treatment for metastatic hepatic leiomyosarcoma associated with STUMP.
4 citations
1 Dec 2010
TL;DR: A case of a primitive EBV-induced liver leiomyosarcoma after renal transplantation is reported, which is probably as the consequence of long term immunosuppression.
Abstract: The incidence of neoplastic complications after solid organ transplantation is increasing tremendously probably as the consequence of long term immunosupression. Beside usual risk factors, the oncogenic role of some viruses like Epstein-Barr virus is well established. We report a case of a primitive EBV-induced liver leiomyosarcoma after renal transplantation.
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2018 | 1 |
| 2010 | 2 |
| 2006 | 1 |
| 1996 | 1 |
| 1991 | 1 |