Journal Article10.1002/CHEM.19970030315
A New Strategy for Oligosaccharide Assembly Exploiting Cyclohexane‐1,2‐diacetal Methodology: An Efficient Synthesis of a High Mannose Type Nonasaccharide
Peter Grice,Steven V. Ley,Jörg Pietruszka,Helen M. I. Osborn,Henning W. M. Priepke,Stuart L. Warriner +5 more
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About: This article is published in Chemistry: A European Journal. The article was published on 20 Jan 2006. The article focuses on the topics: Mannose & Oligosaccharide.
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Citations
Programmable one-pot oligosaccharide synthesis
TL;DR: In this article, the reactivity of a number of p-methylphenyl thioglycoside (STol) donors which are either fully protected or have one hydroxyl group exposed has been quantitatively determined by HPLC in conjunction with the development of a broadly applicable approach for a facile one-pot synthesis of oligosaccharides.
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"One-Pot" Protection, Glycosylation, and Protection-Glycosylation Strategies of Carbohydrates.
Suvarn S. Kulkarni,Cheng-Chung Wang,Narayana Murthy Sabbavarapu,Ananda Rao Podilapu,Pin-Hsuan Liao,Shang-Cheng Hung +5 more
TL;DR: This review describes the methodologies for one- Pot protection and their one-pot glycosylation into the complex glycans and the chronological developments associated with automated syntheses of oligosaccharides.
257
Gold Manno-Glyconanoparticles: Multivalent Systems to Block HIV-1 gp120 Binding to the Lectin DC-SIGN
Olga Martinez-Avila,Karolin Hijazi,Marco Marradi,Caroline Clavel,Colin Campion,Charles Kelly,Soledad Penadés +6 more
TL;DR: A small library of multivalent water-soluble gold glyconanoparticles presenting truncated (oligo)mannosides of the high-mannose undecasaccharide Man(9)GlcNAc(2) and tested them as inhibitors of DC-SIGN binding to gp120, showing more than 20 000-fold increased activity.
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1,2-diacetals: a new opportunity for organic synthesis.
Steven V. Ley,Daniel K. Baeschlin,Darren J. Dixon,Alison C. Foster,Stuart J. Ince,Henning W. M. Priepke,Dominic J. Reynolds +6 more
TL;DR: The use of 1,2-diacetals for a number of synthetic applications to provide diol protection and reactivity control was studied in this article, where the chiral versions of these systems were used to desymmetrize the enantiotopic diol pairs and to discriminate diequatorial diols in many carbohydrate derivatives.
163
References
Use of N-acetylglucosaminyltransferases I and II in the preparative synthesis of oligosaccharides
TL;DR: In this article, 8.8-Methoxycarbonyloctyl 3,6-di-O-[2-O-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-alpha-D mannopyranoyl]-beta-d-mannopyraniumide (1) has been synthesized chemically.
42
Polyclonal antibodies to mannan from yeast also recognize the carbohydrate structure of gp120 of the AIDS virus: an approach to raise neutralizing antibodies to HIV-1 infection in vitro.
Werner E.G. Müller,Heinz C. Schröder,Petra Reuter,Armin Maidhof,Gerd Uhlenbruck,Irvin Winkler +5 more
TL;DR: A mannan preparation from Saccharomyces cerevisiae neutralizing antiserum was raised in rabbits which prevents HIV-1 infection in vitro up to a titre of 1:128 and neutralized the in vitro infectivity down to a concentration of 5 micrograms/ml.
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Substrates for the differentiation of the N-acetylglucosaminytransferases. Synthesis of βDGlcNAc(1 → 2)αDMan(1 → 6)βDMan and βDGlcNAc(1 → 2)αDMan(1 → 6) [αDMan(1 → 3)]βDMan glycosides
S.Hasan Tahir,Ole Hindsgaul +1 more
TL;DR: The trisaccharide βDGlcNAc(1 → 2)αDMan(1 ǫ→ 6)βDMan (2) and the tetrasaccharides βDglc NAc( 1 Ã − 2 )αDMen( 1Ã − 6 )βDMen (3) have been chemically synthesized as their 8-methoxycarbonyloctyl glycosides as discussed by the authors.
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