TL;DR: Examination of apatite formation on a material in SBF is useful for predicting the in vivo bone bioactivity of a material, and the number of animals used in and the duration of animal experiments can be reduced remarkably by using this method.
TL;DR: A review of the properties, biological performance, challenges and future directions of magnesium-based biomaterials can be found in this paper, where the authors explore the properties and challenges of magnesium biomaterial.
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
TL;DR: The most commonly used decellularization methods are described, and consideration give to the effects of these methods upon the biologic scaffold material.
TL;DR: Over the years, a variety of fabrication processes have been developed, resulting in porous implant substrates that can address unresolved clinical problems, and all known methods for fabricating such porous metallic scaffolds are summarized.
TL;DR: Results of this study suggest, that the conclusions drawn from current ASTM standard in vitro corrosion tests cannot be used to predict in vivo corrosion rates of magnesium alloys.
TL;DR: In this paper, a 3D, highly porous, mechanically competent, bioactive and biodegradable scaffolds have been fabricated for the first time by the replication technique using 45S5 Bioglass® powder.
TL;DR: Recent developments and applications of microbial cellulose synthesized in abundance by Acetobacter xylinum in the emerging field of novel wound dressings and skin substitutes are summarized.
TL;DR: Electrospun silk-fibroin-based scaffolds are potential candidates for bone tissue engineering and the mild aqueous process required to spin the fibers offers an important option for delivery of labile cytokines and other components into the system.
TL;DR: The aim of this paper is to review and analyze the current knowledge on ageing process and on its effect on the long term performance of implants in order to distinguish between scientific facts and speculation.
TL;DR: An overview of the complexity of this battleground and of the current and new, in the opinion most promising, strategies in the field of biomaterials to reduce the risks and counteract the establishment of implant infections is offered.
TL;DR: The focus of this review is on the surface engineering aspects of biologically motivated micropatterning of two-dimensional (flat) surfaces with the aim to provide an introductory overview and critical assessment of the many techniques described in the literature.
TL;DR: Stem cell-based tissue engineering using 3D silk fibroin scaffolds has expanded the use of silk-based biomaterials as promising scaffolds for engineering a range of skeletal tissues like bone, ligament, and cartilage, as well as connective tissues like skin.
TL;DR: The results showed that PCL capsules with initial molecular weight of 66000 remained intact in shape during 2-year implantation and broke into low molecular weight pieces at the end of 30 months, confirming that the material did not cumulate in body tissue and could be completely excreted.
TL;DR: The results indicate that cross-linked collagen nanofibers coated with ECM proteins, particularly type I collagen, may be a good candidate for biomedical applications, such as wound dressing and scaffolds for tissue engineering.
TL;DR: Results suggest that PANi-gelatin blend nanofibers might provide a novel conductive material well suited as biocompatible scaffolds for tissue engineering.
TL;DR: It is reported here how freeze casting can be applied to synthesize porous scaffolds exhibiting unusually high compressive strength, e.g. up to 145 MPa for 47% porosity and 65MPa for 56%porosity, which might open the way for hydroxyapatite-based materials designed for load-bearing applications.
TL;DR: Results show that the biodegradable polymer/bioceramic composite scaffolds fabricated by the novel GF/PL method enhance bone regeneration compared with those fabricated byThe conventional SC/PL methods.
TL;DR: In this article, the interaction of opsonins and the macrophage plasma membrane with the surface of a colloidal drug delivery system (CDDS) was investigated. And the authors focused on parameters influencing the interactions of opticins and macrophages.
TL;DR: 3D bioactive glass foam scaffolds sintered at 800 degrees C for 2 h fulfill the criteria for an ideal scaffold for tissue engineering applications and bioactivity is maintained.
TL;DR: Collagen/elastin (1:1) meshes were stabilized by crosslinking with N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS) without altering their original morphology, which afforded materials with a high thermal stability.
TL;DR: Electrospinning studies show that topographical factors designed into biomaterial scaffolds can regulate spreading, orientation, and proliferation of osteoblastic cells.
TL;DR: The development of porous tantalum is in its early stages of evolution and the following represents a review of its biomaterial properties and applications in orthopedic surgery.
TL;DR: The creation of a multifunctional surface can be achieved by co-sputtering the osteoconductive HA with antibacterial Ag with no significant difference in the in vitro cytotoxicty was observed between HA and Ag-HA surfaces.
TL;DR: In vivo rat studies show that HAMC is biocompatible within the intrathecal space for 1 month, and may provide therapeutic benefit, in terms of behavior, as measured by the Basso, Beattie and Bresnahan locomotor scale, and inflammation.
TL;DR: In this study a new method was developed to create 3D cellular structures: sheets of neural cells were layered on each other (layer-by-layer process) by alternate inkjet printing of NT2 cells and fibrin gels.
TL;DR: It is concluded that iron is a suitable metal for the production of a large-size degradable stent with no local or systemic toxicity and a faster degradation rate is desirable.
TL;DR: The polymeric biomaterial PEEK may be a useful biomaterial for interbody fusion cages due to the polymer's increased radiolucency and decreased stiffness.
TL;DR: Micro CT is a more recent method of examining the characteristics of scaffolds and this review aims to highlight this current approach while comparing it with other techniques.
TL;DR: Novel insight shows that not only the capsules material but also the enveloped cells should be hold responsible for loss of a significant portion of the immunoisolated cells and, thus, failure of the grafts on the long term.