Zhen Wang
China Pharmaceutical University
2 Papers
Zhen Wang is an academic researcher from China Pharmaceutical University. The author has contributed to research in topics: Spheroid & Nanocarriers. The author has an hindex of 2, co-authored 2 publications.
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Papers
Optimization of the formation of embedded multicellular spheroids of MCF-7 cells: How to reliably produce a biomimetic 3D model.
Wenli Zhang,Caibin Li,Bruce C. Baguley,Fang Zhou,Weisai Zhou,John Shaw,Zhen Wang,Zimei Wu,Jianping Liu +8 more
TL;DR: A reliable and reproducible method for embedding spheroids using the hanging-drop/agarose method within collagen is described herein and can be used to guide experimental manipulation of 3D cell cultures and to evaluate anticancer drug efficacy.
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Particle morphology: an important factor affecting drug delivery by nanocarriers into solid tumors.
TL;DR: This review will focus on particles with different shapes and the influence of their morphological characteristics on the process of drug delivery to solid tumor in view of systemic circulation, transport from circulation system to tumor tissue, intratumoral transport and uptake by tumor cells, on the basis of introduction of challenges for drug deliveryto solid tumor.
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