Yu-Yang Bi
China Pharmaceutical University
8 Papers
4 Citations
Yu-Yang Bi is an academic researcher from China Pharmaceutical University. The author has contributed to research in topics: Internal medicine & Medicine. The author has an hindex of 1, co-authored 3 publications.
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Papers
Pathological collagen targeting and penetrating liposomes for idiopathic pulmonary fibrosis therapy.
Minghui Yang,Yi-Jun Lin,Meng-Meng Han,Yu-Yang Bi,Xing-Yue He,Lei Xing,Jee-Heon Jeong,Tian-Jiao Zhou,Hualiang Jiang +8 more
TL;DR: Wang et al. as mentioned in this paper constructed pathological collagen targeting and penetrating liposomes (DP-CC) to deliver anti-fibrotic dual drugs including pirfenidone (PFD) and dexamethasone (DEX) deep into injured alveoli.
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Nanoparticles targeting mutant p53 overcome chemoresistance and tumor recurrence in non-small cell lung cancer
Yu-Yang Bi,Qiu Chen,Ming‐Yuan Yang,Lei Xing,Hualiang Jiang +4 more
TL;DR: Researchers developed nanoparticles (FP NPs) that target mutant p53 in non-small cell lung cancer, overcoming chemoresistance and tumor recurrence by degrading mutant p53 and triggering endoplasmic reticulum stress, enhancing cisplatin chemotherapy efficacy.
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Dual Barrier‐Penetrating Inhaled Nanoparticles for Enhanced Idiopathic Pulmonary Fibrosis Therapy
Ming‐Yuan Yang,Meng-Meng Han,Ling Tang,Yu-Yang Bi,Xue-Na Li,Jee‐Heon Jeong,Yi Wang,Hualiang Jiang +7 more
TL;DR: Dual barrier‐penetrating inhaled liposomes are constructed utilizing tris‐(2‐carboxyethyl)‐phosphine (TCEP) and l‐arginine to penetrate the mucus and ECM barriers, respectively to improve the efficacy of IPF treatment.
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Dual inhibition of glucose uptake and energy supply synergistically restrains the growth and metastasis of breast cancer
Yuan-xi Xu,Liling Huang,Yu-Yang Bi,Qi Song,Mengmeng Zhang,Lingfeng Zhang,Tian-Jiao Zhou,Lei Xing,Hulin Jiang +8 more
TL;DR: In this article , a nanoplatform with dual-inhibition of glucose uptake and oxidative phosphorylation (OXPHOS) was designed, which consisted of albendazole (ABZ) and atovaquone (ATO) by simple carrier-free self-assembling.
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Tetrazine-mediated bioorthogonal removal of 3-isocyanopropyl groups enables the controlled release of nitric oxide in vivo.
Jianbing Wu,Jianbing Wu,Tao Sun,Tao Sun,Chenxi Yang,Tian Lv,Yu-Yang Bi,Yuan Xu,Yong Ling,Jun Zhao,Rigang Cong,Yihua Zhang,Jianhua Wang,Hao Wen,Jiang Hulin,Jiang Hulin,Fei Li,Zhangjian Huang,Zhangjian Huang +18 more
TL;DR: In this paper, a class of O2-3-isocyanopropyl diazeniumdiolates 3a-f was described as new bioorthogonal NO precursors, which can be effectively uncaged via tetrazine-mediated bond cleavage reactions to liberate NO and acrolein in living cancer cells, exhibiting potent antiproliferative activity.
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