Yonghua Xing
Peking Union Medical College
8 Papers
38 Citations
Yonghua Xing is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Oxidative stress & Total body irradiation. The author has an hindex of 6, co-authored 8 publications.
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Papers
Metformin ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice.
Guo-Shun Xu,Hongying Wu,Junling Zhang,Deguan Li,Yueying Wang,Yingying Wang,Heng Zhang,Lu Lu,Chengcheng Li,Song Huang,Yonghua Xing,Daohong Zhou,Daohong Zhou,Aimin Meng +13 more
TL;DR: Findings demonstrate that resveratrol can protect HSCs from radiation at least in part via activation of Sirt1 and has the potential to be used as an effective therapeutic agent to ameliorate TBI-induced long-term BM injury.
194
Radioprotective and Antioxidant Effect of Resveratrol in Hippocampus by Activating Sirt1
Jianguo Li,Li Feng,Yonghua Xing,Yan Wang,Liqing Du,Chang Xu,Jia Cao,Qin Wang,Saijun Fan,Qiang Liu,Feiyue Fan +10 more
TL;DR: The results provide evidence that the mitochondrial protection and the antioxidant effect of resveratrol contribute to metabolic activity, and suggest that Sirt1 may play an important role to protect neurons from oxidative stress.
Mitigating the Effects of Xuebijing Injection on Hematopoietic Cell Injury Induced by Total Body Irradiation with γ rays by Decreasing Reactive Oxygen Species Levels
Deguan Li,Lu-De Lu,Junling Zhang,Xiao-Chun Wang,Yonghua Xing,Hongying Wu,Xiangdong Yang,Zhexin Shi,Mingfeng Zhao,Saijun Fan,Aimin Meng +10 more
TL;DR: XBJ enhances the survival rate of irradiated mice and attenuates the effects of radiation on hematopoietic injury by decreasing ROS production in BM cells, indicating that XBJ may be a promising therapeutic candidate for reducing hematopolietic radiation injury.
34
Identification of specific gene modules in mouse lung tissue exposed to cigarette smoke.
Yonghua Xing,Zhang Junling,Lu Lu,Deguan Li,Yueying Wang,Song Huang,Chengcheng Li,Zhu-Bo Zhang,Jian-Guo Li,Guo-Shun Xu,Meng Aimin +10 more
TL;DR: Specific gene modules may provide better understanding of molecular mechanisms, and hub genes are potential candidates of therapeutic targets that may possible improve development of novel treatment approaches.
6
Patent
Application of DPP4 inhibitor in medicines for preventing and treating radiation-induced myelosuppression
Deguan Li,Meng Aimin,Lu Lu,Zhang Junling,Yueying Wang,Wu Hongying,Xiao-Chun Wang,Song Huang,Chengcheng Li,Yonghua Xing,Saijun Fan +10 more
- 28 Oct 2015
TL;DR: In this paper, a new application method of a DPP4 inhibitor as a medicine for preventing or treating radiation-induced myelosuppression was disclosed. But this method is not suitable for mice.