Yildirim Sara
Hacettepe University
45 Papers
163 Citations
Yildirim Sara is an academic researcher from Hacettepe University. The author has contributed to research in topics: Neurotransmission & Contractility. The author has an hindex of 18, co-authored 40 publications. Previous affiliations of Yildirim Sara include University of Texas Southwestern Medical Center.
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Papers
An Isolated Pool of Vesicles Recycles at Rest and Drives Spontaneous Neurotransmission
TL;DR: It is shown that synaptic vesicles recycle at rest, and after spontaneous exo-endocytosis, they populate a reluctantly releasable pool of limited size, and that in the absence of the vesicle SNARE protein synaptobrevin (VAMP), activity-dependent and spontaneously recycling vESicles could mix, suggesting a role for synaptotagmin-1 in the separation of the two pools.
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Development of Vesicle Pools during Maturation of Hippocampal Synapses
TL;DR: This analysis suggests that presynaptic boutons go through three distinct functional states to mature, and exposes a mechanism that ensures functionally effective allocation of a limited number of vesicles in a CNS synapse.
224
Persistent Defect in Transmitter Release and Synapsin Phosphorylation in Cerebral Cortex After Transient Moderate Ischemic Injury
TL;DR: Data demonstrate that synaptic transmission may be permanently impaired after transient moderate brain injury, and the transmission failure is likely to be caused by presynaptic mechanisms, one of which may be impaired phosphorylation of Presynaptic proteins.
117
Phorbol Esters Target the Activity-Dependent Recycling Pool and Spare Spontaneous Vesicle Recycling
TL;DR: It is suggested that priming mechanisms that prepare vesicles for fusion, which are targeted by phorbol esters, are different for the spontaneous and evoked forms of fusion.
49
Low dose simvastatin induces compositional, structural and dynamic changes in rat skeletal extensor digitorum longus muscle tissue.
TL;DR: The effects of low dose simvastatin, a lipophilic statin, on rat EDL muscle were investigated at the molecular level using FTIR (Fourier-transform infrared) spectroscopy, which revealed a significant decrease in lipid, nucleic acid, protein and glycogen content and a significant increase in beta-sheet structure.
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