Xinghuai Sun
Fudan University Shanghai Medical College
10 Papers
18 Citations
Xinghuai Sun is an academic researcher from Fudan University Shanghai Medical College. The author has contributed to research in topics: Medicine & Oxidative stress. The author has an hindex of 7, co-authored 10 publications. Previous affiliations of Xinghuai Sun include Fudan University & National Health and Family Planning Commission.
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Papers
Inducible nitric oxide synthase-mediated alteration of mitochondrial OPA1 expression in ocular hypertensive rats.
Yi Dai,Robert N. Weinreb,Keunyoung Kim,Duy Nguyen,Sang Woo Park,Xinghuai Sun,James D. Lindsey,Mark H. Ellisman,Won-Kyu Ju +8 more
TL;DR: Findings suggest that mitochondrial preservation after inhibition of NOS-2 may be useful for protecting RGCs against glaucomatous damage and an increase in mitochondrial OPA1 may provide an important cellular defense mechanism against pressure-mediated retinal damage.
The association between serum uric acid and glaucoma severity in primary angle closure glaucoma: a retrospective case-control study.
TL;DR: Significantly lower serum UA concentration in PACG and its negative association with disease severity presented it as an important candidate in reaction to oxidative stress in glaucoma pathogenesis.
31
AAV-mediated gene transfer of human X-linked inhibitor of apoptosis protects against oxidative cell death in human RPE cells
Haidong Shan,Dan Ji,Alun R. Barnard,Daniel M. Lipinski,Qisheng You,Edward Lee,Tengku Ain Kamalden,Xinghuai Sun,Robert E MacLaren,Robert E MacLaren +9 more
TL;DR: Overexpression of human XIAP protects ARPE-19 cells against H(2)O(2)-induced oxidative cell death by acting downstream on the apoptotic pathway and may provide a means of reducing the effect of oxidative stress to RPE cells in age-related macular degeneration.
19
Relationship between ocular biometry and severity of primary angle-closure glaucoma: relevance for predictive, preventive, and personalized medicine
TL;DR: The AL was positively and significantly related to the severity of PACG in female but not male subjects and suggests the use of AL assessment in glaucoma monitoring, diagnosis, and progression.
16
Analysis of medical expenditure and socio-economic status in patients with ocular chemical burns in East China: a retrospective study
TL;DR: The medical expense was a huge economic burden to most victims of ocular chemical burns, and personal and household per capita income of the victims decreased significantly after injury, both of which had a close relationship with the injury severity.