Xinbing Wei
Shandong University
56 Papers
146 Citations
Xinbing Wei is an academic researcher from Shandong University. The author has contributed to research in topics: Reperfusion injury & Neuroprotection. The author has an hindex of 26, co-authored 56 publications.
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Papers
NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke
Fan Yang,Ziying Wang,Xinbing Wei,Huirong Han,Xianfang Meng,Yan Zhang,Weichen Shi,Fengli Li,Tao Xin,Qi Pang,Fan Yi +10 more
TL;DR: It is found that NLRP3 deficiency ameliorated cerebral injury in mice after ischemic stroke by reducing infarcts and blood–brain barrier (BBB) damage and that NOX2 deficiency improved outcomes after ischemia stroke by mediatingNLRP3 signaling.
412
Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.
Min Liu,Kaili Liang,Junhui Zhen,Meng Zhou,Xiaojie Wang,Ziying Wang,Xinbing Wei,Yan Zhang,Yu Sun,Zhuanli Zhou,Hua Su,Chun Zhang,Ningjun Li,Chengjiang Gao,Jun Peng,Fan Yi +15 more
TL;DR: It is shown that histone deacetylase Sirt6 protects podocytes from apoptosis and inflammation by increasing autophagic flux through inhibition of the Notch pathway.
301
Histone deacetylase 4 selectively contributes to podocyte injury in diabetic nephropathy
Xiaojie Wang,Jiang Liu,Junhui Zhen,Chun Zhang,Qiang Wan,Guangyi Liu,Xinbing Wei,Yan Zhang,Ziying Wang,Huirong Han,Huiyan Xu,Chanchan Bao,Zhenyu Song,Xiumei Zhang,Ningjun Li,Fan Yi +15 more
TL;DR: HDAC4 contributes to podocyte injury and is one of critical components of a signal transduction pathway that links renal injury to autophagy in diabetic nephropathy.
228
TREM2 overexpression attenuates neuroinflammation and protects dopaminergic neurons in experimental models of Parkinson's disease.
TL;DR: The role of TREM2 in the 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine mouse model of PD suggested to have important neuroprotective effects against PD by critically modulating neuroinflammatory responses.
104
Eriodictyol protects against H2O2-induced neuron-like PC12 cell death through activation of Nrf2/ARE signaling pathway
TL;DR: It is suggested that eriodictyol upregulates HO-1 and γ-GCS expression through the activation of Nrf2/ARE pathway and protects PC12 cells against H(2)O(2)-induced oxidative stress.
72