Xiaoqing Hu
Peking University
122 Papers
283 Citations
Xiaoqing Hu is an academic researcher from Peking University. The author has contributed to research in topics: Cartilage & Medicine. The author has an hindex of 24, co-authored 90 publications.
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Papers
Structurally and Functionally Optimized Silk-Fibroin–Gelatin Scaffold Using 3D Printing to Repair Cartilage Injury In Vitro and In Vivo
Weili Shi,Muyang Sun,Xiaoqing Hu,Bo Ren,Jin Cheng,Chenxi Li,Xiaoning Duan,Xin Fu,Jiying Zhang,Haifeng Chen,Yingfang Ao +10 more
TL;DR: This dually optimized scaffold has shown superior performance for cartilage repair in a knee joint because it not only retains adequate BMSCs, due to efficient recruiting ability, and acts as a physical barrier for blood clots, but also provides a mechanical protection before neocartilage formation.
456
A small molecule promotes cartilage extracellular matrix generation and inhibits osteoarthritis development.
Yuanyuan Shi,Xiaoqing Hu,Jin Cheng,Xin Zhang,Fengyuan Zhao,Weili Shi,Bo Ren,Huilei Yu,Peng Yang,Zong Li,Qiang Liu,Zhenlong Liu,Xiaoning Duan,Xin Fu,Jiying Zhang,Jianquan Wang,Yingfang Ao +16 more
TL;DR: It is shown that BNTA, a small molecule identified in a chemical screen, promotes ECM generation in human osteoarthritic chondrocytes and cartilage explants, and suppresses pathology in a rat model of osteOarthritis.
Bone marrow mesenchymal stem cell-derived exosomes promote tendon regeneration by facilitating the proliferation and migration of endogenous tendon stem/progenitor cells.
Huilei Yu,Jin Cheng,Weili Shi,Bo Ren,Fengyuan Zhao,Yuanyuan Shi,Peng Yang,Xiaoning Duan,Jiying Zhang,Xin Fu,Xiaoqing Hu,Yingfang Ao +11 more
TL;DR: It is demonstrated that the application of BMSCs-derived exosomes might be a promising approach to activate the regenerative potential of endogenous TSPCs in tendon injured region, and fibrin-exosomes delivery system represents a successful local treatment strategy of exosome.
179
The tissue origin effect of extracellular vesicles on cartilage and bone regeneration.
TL;DR: In this article, the authors investigate the impact of the tissue origin of mesenchymal stem cells on the therapeutic bioactivity of their corresponding extracellular vesicles for cartilage and bone regeneration.
134
A composite scaffold of MSC affinity peptide-modified demineralized bone matrix particles and chitosan hydrogel for cartilage regeneration
Qingyang Meng,Zhentao Man,Linghui Dai,Hongjie Huang,Xin Zhang,Xiaoqing Hu,Zhenxing Shao,Jingxian Zhu,Jiying Zhang,Xin Fu,Xiaoning Duan,Yingfang Ao +11 more
TL;DR: The functional composite scaffold of DBM-E7/CS is a promising option for repairing irregularly shaped cartilage defects and exhibited translucent and superior cartilage-like structures after implantation in vivo for four weeks.