Xiangjun Chen
Binzhou University
17 Papers
12 Citations
Xiangjun Chen is an academic researcher from Binzhou University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 2, co-authored 3 publications.
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Papers
On-demand pH-sensitive surface charge-switchable polymeric micelles for targeting Pseudomonas aeruginosa biofilms development
TL;DR: Zhang et al. as mentioned in this paper constructed pH-sensitive surface charge-switchable azithromycin (AZM)-encapsulated micelles (denoted as AZM-SCSMs), which can act as therapeutic agent for treating Pseudomonas aeruginosa biofilms.
Elaboration on the architecture of pH-sensitive surface charge-adaptive micelles with enhanced penetration and bactericidal activity in biofilms.
TL;DR: Wang et al. as mentioned in this paper synthesized three types of pH-sensitive copolymers based on poly (β-amino ester) (PAE), poly (lactic-co-glycolic acid) (PLA) and polyethylene glycol (PEG), PAE-PLA-mPEG (A-L-E), PLA-PAE-m PEG (L-A-E) and PLA-PEGPAE (LE-A) to address this issue.
On-Demand Multifunctional Electrostatic Complexation for Synergistic Eradication of MRSA Biofilms.
TL;DR: Based on the comprehensive evaluation of the therapeutic outcome, the electrostatic complexation (TDZ-G4@CA) can serve as a promising strategy for enhanced antibiotic therapy for combating biofilm-associated infections.
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Free-Radical Cascade Generated by AIPH/Fe3O4-Coloaded Nanoparticles Enhances MRI-Guided Chemo/Thermodynamic Hypoxic Tumor Therapy.
Wenting Li,Baoyuan Li,Bin Wu,Baocheng Tian,Xiangjun Chen,Changrong Wang,W. Hong,Jinrong Peng +7 more
TL;DR: This study provides an alternative method for the generation of an oxygen-independent free-radical cascade for tumor co-therapy guided by magnetic resonance imaging PTT/TDT.
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Step-by-step dual stimuli-responsive nanoparticles for efficient bacterial biofilm eradication
TL;DR: In this article, a step-by-step dual stimuli-responsive azithromycin-loaded nanoparticles (CM/AZM@Tyr) was constructed for efficient biofilm eradication by self-assembly of poly(e-caprolactone)-polyethylene glycol-polyethylenimine (PCL-PEG-PEI) into cationic micelles and simultaneously encapsulated AZM into the hydrophobic core, which is further bound with cis-aconityl-D-tyrosine (CA-Tyr),
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