Thomas Rau
University of Hamburg
57 Papers
442 Citations
Thomas Rau is an academic researcher from University of Hamburg. The author has contributed to research in topics: Internal medicine & Heart failure. The author has an hindex of 33, co-authored 54 publications. Previous affiliations of Thomas Rau include University of Erlangen-Nuremberg.
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Papers
Detection of Circulating Tumor Cells in Peripheral Blood of Patients with Metastatic Breast Cancer: A Validation Study of the CellSearch System
Sabine Riethdorf,Herbert A. Fritsche,Volkmar Müller,Thomas Rau,Christian Schindlbeck,Brigitte Rack,Wolfgang Janni,Cornelia Coith,Katrin Beck,Fritz Jänicke,S. Jackson,Terrie G. Gornet,Massimo Cristofanilli,Klaus Pantel +13 more
TL;DR: The CellSearch system enables the reliable detection of CTCs in blood and is suitable for the routine assessment of metastatic breast cancer patients in the clinical laboratory.
1.3K
Detection and HER2 Expression of Circulating Tumor Cells: Prospective Monitoring in Breast Cancer Patients Treated in the Neoadjuvant GeparQuattro Trial
Sabine Riethdorf,Volkmar Müller,Liling Zhang,Thomas Rau,Sibylle Loibl,Martina Komor,Marc Roller,Jens Huober,Tanja Fehm,Iris Schrader,Jörn Hilfrich,Frank Holms,Hans Tesch,Holger Eidtmann,Michael Untch,Gunter von Minckwitz,Klaus Pantel +16 more
TL;DR: CTC number was low in patients with primary breast cancer and the decrease in CTC incidence during treatment was not correlated with standard clinical characteristics and primary tumor response, and there was no association between tumor response to NT and CTC detection.
502
Human engineered heart tissue as a versatile tool in basic research and preclinical toxicology.
Sebastian Schaaf,Aya Shibamiya,Marco Mewe,Alexandra Eder,Andrea Stöhr,Marc N. Hirt,Thomas Rau,Wolfram-Hubertus Zimmermann,Lenard Conradi,Thomas Eschenhagen,Arne Hansen +10 more
TL;DR: This study establishes hEHT as a simple in vitro model for heart research and describes a simple and robust protocol for the generation of fibrin-based human engineered heart tissue in a 24-well format using an unselected population of differentiated human embryonic stem cells containing 30–40% α-actinin-positive cardiac myocytes.
Changes in Cytoskeletal Protein Composition Indicative of an Epithelial-Mesenchymal Transition in Human Micrometastatic and Primary Breast Carcinoma Cells
Birthe Willipinski-Stapelfeldt,Sabine Riethdorf,Volker Assmann,Ute Woelfle,Thomas Rau,Guido Sauter,Jochen Heukeshoven,Klaus Pantel +7 more
TL;DR: Micrometastatic cancer cells exhibit marked changes in the expression pattern of cytoskeletal proteins indicative of an epithelial-mesenchymal transition, which could already be detected in primary tumors and is associated with the aggressive behavior of breast cancer cells in vivo.
341
CYP2D6 Genotype: Impact on Adverse Effects and Nonresponse During Treatment with Antidepressants—a Pilot Study
Thomas Rau,Gerlinde Wohlleben,Henrike Wuttke,Norbert Thuerauf,Jens Lunkenheimer,Mario Lanczik,Thomas Eschenhagen +6 more
TL;DR: This association study investigated whether the CYP2D6 genotype distribution differs from that of the German white population either in patients with marked adverse effects or in nonresponders during treatment with antidepressants metabolized by CYP 2D6.
209