Sun Yilin

TL;DR: According to a Janus kinase 3 inhibitor disclosed by the inventor, the therapeutic effects on RA (rheumatoid arthritis), psoriasis and other autoimmune diseases can be obviously improved, and the inhibitor has excellent JAK3 inhibitory activity as mentioned in this paper.

TL;DR: In this article, a method for synthesizing a doxercalciferol analog WXFQ-65 was proposed, in which an excessive amount of the halogenating agent is used to perform halogenations on the doxerciferols, and a final product is prepared through hydrolysis and recrystallization.

TL;DR: In this paper, the authors provided a synthesis method of pidotimod disclosed as Formula, which comprises the following steps: (1) carrying out condensation reaction on thioproline and cyprolidol under the actions of a catalyst and a condense reaction solvent to obtain an intermediate I; (2) carryingout condensation reactions on the intermediate I and pyroglutamic acid under the action of a catalytic catalyst and an acid solvent to get an intermediate II; and (3) dropwisely adding an acidic material into the intermediate II, and

TL;DR: In this article, the authors provided a doxercalciferol analogue WXFQ-65 and a synthetic method thereof, which comprises the steps of carrying out halogenating reaction on vitamin D2 in an organic solvent, adding a hydrolysis reagent to generate Hydrolysis reaction under an acidic condition, and carrying out chromatographic separation.