The invention provides a compound shown in the formula (I) or pharmaceutically accepted salt; further, the invention also discloses a drug composition containing the formula (I) and application. According to a Janus kinase 3 inhibitor disclosed by the invention, the therapeutic effects on RA (rheumatoid arthritis), psoriasis and other autoimmune diseases can be obviously improved, and the inhibitor has excellent JAK3 inhibitory activity.

Janus kinase 3 inhibitor

The invention provides an endocyclicg compound with Janus kinase inhibition activity, which is a compound or pharmaceutically acceptable salt shown as the following formula (I). The invention simultaneously discloses a drug composition containing the compound shown as the formula I, and applications.

Endocyclic compound with Janus kinase inhibition activity

The invention provides a pharmaceutic preparation for treating arthritis and a preparing method thereof. The pharmaceutic preparation comprises a compound (I) and functional auxiliary materials, wherein the functional auxiliary materials comprise a framework material, a disintegrating agent, a release regulator and a lubricating agent. The pharmaceutic preparation has the advantages that the pharmaceutic preparation is simple to prepare, low in cost and convenient to use, the compound (I) can serve as a JAK inhibitor and can be fast absorbed to bring the curative effect of the main medicine into play, the defect of slow action of an existing preparation can be overcome, and the pharmaceutic preparation is definite and lasting in curative effect, capable of reducing administration times, stable in blood concentration and small in side effects.

Pharmaceutic preparation for treating arthritis and preparing method thereof

The invention discloses a pharmaceutical composition for treating psoriasis. The pharmaceutical composition consists of a compound and auxiliary materials, wherein the compound has a structure shown in the specification and has the effect of treating psoriasis.

Pharmaceutical composition for treating psoriasis and preparation method thereof

The invention discloses an isobenzazole-1-ketone compound having an anti-inflammatory activity, and provides a compound shown in the formula (I) or a pharmaceutically acceptable salt of the compound.The disclosed isobenzazole-1-ketone compound having the anti-inflammatory activity obviously strengthens the drug targeting, and achieves better treatment effects on the diseases like multiple myelomaand rheumatoid arthritis.

Isobenzazole-1-ketone compound having anti-inflammatory activity

The invention provides a compound shown as formula (I) or a pharmaceutically acceptable salt thereof. The invention also discloses a drug compound containing the compound shown as formula I and an application thereof.

Jak kinase inhibitor

Popular Tasks used by Researchers

How can I help with your research?

Get more enhanced response by uploading the PDFs you want me to reference.

No relevant PDFs in your library

SciSpace is the AI research assistant for academics. Run systematic literature reviews on 280M+ papers, and write papers with cited sources. Trusted by 1M+ students, PhDs & researchers.

SciSpace | AI for Research

We encountered an error while loading the panel. Please try refreshing the page.

Something went wrong

Analyze PDFs

Code & Manuscripts

Funding & Grants

Literature & Patents

Medical & Clinical Data

Systematic Review

Visualize & Present

Web & Data

Build a Google Scholar-like website for your research.

Build a website

Create charts and images for your research

Create a Chart

Write a paper for submission to a journal

Draft a manuscript

Patent Search

Design eye-catching scientific posters in minutes.

Scientific Poster Generation

Systematic Literature Review

Anyone with the link can view this chat. You can switch it back to private anytime.

One task is running at the moment. Your messages will be shown right after.

Drag and drop or click here to browse

Loved by <highlight>1 million+</highlight> researchers

Extract a list of specific topics and their sources from unstructured text

Topics

Compare and analyze relevant papers that matches with your search

Papers

Get insights from PDFs and bookmarked papers from your library

My library

Recent searches

Try searching for:

Catch AI-generated content in scholarly and non-scholarly content

{ai} Detector

Ai Writer

Get PDF Summaries, highlighted text explanations 

Chat with PDF

Effortlessly create in-text citations and bibliographies in APA and 2,500 other formats

Citation generator

Get explanations, summaries, and answers on academic papers

Ease up your research workflow with {scispace}'s cohort of exciting AI tools

Elevate your academic writing skills and convey your ideas the way you want

Paraphraser

Explore our range of reading and writing tools

Your file is being prepared and should be ready in a few minutes. If it's a large file, it might take a bit longer. You can close this window, and we'll email you the file when it's done.

You have reached a maximum limit of <strong>{limit}</strong> columns in the table. Remove at least <strong>1</strong> column to add or create another one.

Sun Yilin

Author Tools

Chat about Author

Papers

Jak kinase inhibitor