Steven Walker
University of Bristol
151 Papers
610 Citations
Steven Walker is an academic researcher from University of Bristol. The author has contributed to research in topics: Medicine & Mental health. The author has an hindex of 26, co-authored 136 publications. Previous affiliations of Steven Walker include University Hospital of Wales & Boston Children's Hospital.
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Papers
The Warwick Agreement on femoroacetabular impingement syndrome (FAI syndrome): an international consensus statement
Damian R. Griffin,Edward J. Dickenson,Edward J. Dickenson,Jude O'donnell,Rintje Agricola,Tariq M Awan,M. Beck,John C. Clohisy,H P Dijkstra,Eanna Falvey,Mo Gimpel,Rana S Hinman,Per Hölmich,Ara Kassarjian,Hal David Martin,RobRoy L. Martin,Richard C. Mather,Marc J. Philippon,Michael P. Reiman,Amir Takla,Kristian Thorborg,Steven Walker,Adam Weir,Kim L Bennell +23 more
TL;DR: The 2016 Warwick Agreement on femoroacetabular impingement syndrome was convened to build an international, multidisciplinary consensus on the diagnosis and management of patients with FAI syndrome.
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Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer.
Eileen Parkes,Steven Walker,Laura E. Taggart,Nuala McCabe,Laura A. Knight,Richard D A Wilkinson,Karen D. McCloskey,Niamh E. Buckley,Kienan I. Savage,Manuel Salto-Tellez,Stephen McQuaid,Mary T. Harte,Paul B. Mullan,D. Paul Harkin,Richard D. Kennedy +14 more
TL;DR: A novel mechanism of immune infiltration in DDRD tumors, independent of neoantigen production is proposed, and activation of this pathway and associated PD-L1 expression may explain the paradoxical lack of T-cell-mediated cytotoxicity observed in DDRd tumors.
Outpatient Talc Administration by Indwelling Pleural Catheter for Malignant Effusion
Rahul Bhatnagar,Emma Keenan,Anna J Morley,Brennan C Kahan,Andrew E. Stanton,Mohammed Haris,Richard Harrison,Rehan A. Mustafa,Lesley Bishop,Liju Ahmed,Alex West,J Holme,Matthew Evison,Mohammed Munavvar,Pasupathy Sivasothy,Jurgen Herre,David Cooper,Mark Roberts,Anur Guhan,Clare E Hooper,James R. Walters,Tarek Saba,Biswajit Chakrabarti,Samal Gunatilake,Ioannis Psallidas,Steven Walker,Anna C. Bibby,Sarah Smith,Louise Stadon,Natalie Zahan-Evans,Y. C. Gary Lee,John E Harvey,Najib M. Rahman,Robert F. Miller,Nick A Maskell +34 more
TL;DR: Among patients without substantial lung entrapment, the outpatient administration of talc through an indwelling pleural catheter for the treatment of malignant pleural effusion resulted in a significantly higher chance of pleurodesis at 35 days than an ind welling catheter alone, with no deleterious effects.
Development and Independent Validation of a Prognostic Assay for Stage II Colon Cancer Using Formalin-Fixed Paraffin-Embedded Tissue
Richard D. Kennedy,Max Bylesjö,Peter Kerr,Timothy Davison,Julie Black,Elaine W. Kay,Robert J Holt,Vitali Proutski,Miika Ahdesmaki,V. M. Farztdinov,Nicolas Goffard,Peter Hey,F. A. McDyer,Karl Mulligan,Julie Mussen,Eamonn J. O'Brien,Gavin R. Oliver,Steven Walker,Jude M. Mulligan,Claire Wilson,Andreas Winter,Diarmuid O'Donoghue,Hugh Mulcahy,Jacintha O'Sullivan,Kieran Sheahan,John Hyland,Rajiv Dhir,Oliver F. Bathe,Ola Winqvist,Upender Manne,Chandrakumar Shanmugam,Sridhar Ramaswamy,Eduardo J. Leon,William I. Smith,Ultan McDermott,Richard H. Wilson,Daniel B. Longley,John L. Marshall,Robert Cummins,Daniel J. Sargent,Patrick G. Johnston,D. Paul Harkin +41 more
TL;DR: This gene signature represents a novel prognostic biomarker for patients with stage II colon cancer that can be applied to FFPE tumor samples that was shown to perform independently from known prognostic factors.
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Calpain 2 and Src dependence distinguishes mesenchymal and amoeboid modes of tumour cell invasion: a link to integrin function
Neil O. Carragher,Steven Walker,L A Scott Carragher,Fiona Harris,Tomi K. Sawyer,Valerie G. Brunton,Bradford W. Ozanne,Margaret C. Frame +7 more
TL;DR: Findings link weakened integrin function to a lack of requirement for calpain 2-mediated integrin adhesion turnover during amoeboid invasion, which means mesenchymal invasion is uniquely sensitive to Src inhibitors.
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