Stephanie Gaillard
Johns Hopkins University
92 Papers
457 Citations
Stephanie Gaillard is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 21, co-authored 71 publications. Previous affiliations of Stephanie Gaillard include Durham University & Rutgers University.
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Papers
HDAC6 Regulates Hsp90 Acetylation and Chaperone-Dependent Activation of Glucocorticoid Receptor
Jeffrey J. Kovacs,Patrick J. Murphy,Stephanie Gaillard,Xuan Zhao,June-Tai Wu,Christopher V. Nicchitta,Minoru Yoshida,David O. Toft,William B. Pratt,Tso-Pang Yao +9 more
TL;DR: In this article, the deacetylase HDAC6 was shown to be a target of the molecular chaperone heat shock protein 90 (Hsp90) and its accessory cochaperones.
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Estrogen-related Receptors Stimulate Pyruvate Dehydrogenase Kinase Isoform 4 Gene Expression
Yi Zhang,Ke Ma,Prabodh Sadana,Farhana Chowdhury,Stephanie Gaillard,Fang Wang,Donald P. McDonnell,Terry G. Unterman,Marshall B. Elam,Marshall B. Elam,Edwards A. Park +10 more
TL;DR: A key role for the ERRs is demonstrated in the induction of hepatic PDK4 gene expression in hepatoma cells, suggesting a novel role for ERRs in controlling pyruvate metabolism.
173
Inhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-Induced Cytotoxicity in Ovarian Cancer Cells by Stabilizing Microtubules.
Yu Yu,Stephanie Gaillard,Jude M. Phillip,Tai-Chung Huang,Sneha M. Pinto,Nayara G. Tessarollo,Nayara G. Tessarollo,Zhen Zhang,Akhilesh Pandey,Denis Wirtz,Ayse Ayhan,Ayse Ayhan,Ben Davidson,Ben Davidson,Tian Li Wang,Ie Ming Shih +15 more
TL;DR: It is reported that recurrent ovarian carcinomas after paclitaxel/carboplatin treatment have higher levels of spleen tyrosine kinase (SYK) and phospho-SYK, and targeting SYK pathway is a promising strategy to enhance pac litaxel response.
138
Molecular Classification and Emerging Targeted Therapy in Endometrial Cancer.
TL;DR: The current molecular landscape of endometrial cancers is described, efforts underway to incorporate molecular alterations into the current classification systems, and the development of diagnostic tools for the early detection ofendometrial cancer are described.
125
Identification and Structure−Activity Relationship of Phenolic Acyl Hydrazones as Selective Agonists for the Estrogen-Related Orphan Nuclear Receptors ERRβ and ERRγ
William J. Zuercher,Stephanie Gaillard,Lisa A. Orband-Miller,Esther Y. Chao,Barry G. Shearer,David G Jones,Aaron B. Miller,Jon L. Collins,Donald P. McDonnell,Timothy M. Willson +9 more
TL;DR: The first small molecule agonists of the estrogen-related receptors have been identified and show binding to ERRgamma with remarkable selectivity over the classical estrogen receptors.
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