Siobhán B. Carr
National Institutes of Health
109 Papers
225 Citations
Siobhán B. Carr is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Medicine & Cystic fibrosis. The author has an hindex of 25, co-authored 91 publications. Previous affiliations of Siobhán B. Carr include Royal Brompton & Harefield NHS Foundation Trust & Great Ormond Street Hospital.
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Papers
Multiple-Breath Washout as a Marker of Lung Disease in Preschool Children with Cystic Fibrosis
Paul Aurora,Andrew Bush,Per M. Gustafsson,C Oliver,Colin Wallis,Jack Price,John Stroobant,Siobhán B. Carr,Janet Stocks +8 more
TL;DR: Children with CF who were infected with Pseudomonas aeruginosa had significantly higher lung clearance index, but no significant difference in other lung function measures, when compared with noninfected children.
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Early detection of cystic fibrosis lung disease: multiple-breath washout versus raised volume tests
Sooky Lum,Per M. Gustafsson,Henrik Ljungberg,Georg Hülskamp,Andrew Bush,Siobhán B. Carr,Rosemary Castle,Ah-Fong Hoo,Jack F. Price,Sarath Ranganathan,John Stroobant,Angie Wade,Colin Wallis,Hilary Wyatt,Janet Stocks +14 more
TL;DR: The findings support the view that inflammatory and/or structural changes in the airways of children with cystic fibrosis start early in life, and have important implications regarding early detection and interventions.
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Lung Clearance Index and HRCT are complementary markers of lung abnormalities in young children with CF
Catherine M. Owens,Paul Aurora,Sanja Stanojevic,Andrew Bush,Angie Wade,C Oliver,Alistair Calder,John Price,Siobhán B. Carr,Adarsh Shankar,Janet Stocks +10 more
TL;DR: Whether the lung clearance index derived from multiple breath inert-gas washout is as effective as HRCT in identifying pulmonary abnormalities in young children with CF is assessed and complimentary information may be gained in individual patients.
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Randomised controlled trial of nasal continuous positive airways pressure (CPAP) in bronchiolitis.
TL;DR: This study suggests that CPAP compared with ST improves ventilation in children with bronchiolitis and hypercapnoea.
194
De Novo Mutations in FOXJ1 Result in a Motile Ciliopathy with Hydrocephalus and Randomization of Left/Right Body Asymmetry.
Julia Wallmeier,Diana Frank,Amelia Shoemark,Tabea Nöthe-Menchen,Sandra Cindric,Heike Olbrich,Niki T. Loges,Isabella Aprea,Gerard W. Dougherty,Petra Pennekamp,Thomas Kaiser,Hannah M. Mitchison,Claire Hogg,Siobhán B. Carr,Maimoona A. Zariwala,Thomas W. Ferkol,Margaret W. Leigh,Stephanie D. Davis,Jeffrey J. Atkinson,Susan K. Dutcher,Michael R. Knowles,Holger Thiele,Janine Altmüller,Henrike Krenz,Marius Wöste,Angela Brentrup,Frank Ahrens,Christian Vogelberg,Deborah J. Morris-Rosendahl,Heymut Omran +29 more
TL;DR: In this paper, the authors identified an autosomal-dominant cause of a distinct motile ciliopathy related to defective ciliogenesis of the ependymal cilia in six individuals.
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