Shigeru Noguchi
9 Papers
37 Citations
Shigeru Noguchi is an academic researcher. The author has contributed to research in topics: Adherens junction & Neurogenesis. The author has an hindex of 8, co-authored 9 publications.
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Papers
Inactivation of aPKCλ results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex
Fumiyasu Imai,Syu-ichi Hirai,Kazunori Akimoto,Hiromichi Koyama,Takaki Miyata,Masaharu Ogawa,Shigeru Noguchi,Toshikuni Sasaoka,Tetsuo Noda,Shigeo Ohno +9 more
TL;DR: It is concluded that, at least in the later stages of neurogenesis, regulation of cell cycle exit is independent of adherens junctions.
Methyl CpG-binding protein isoform MeCP2_e2 is dispensable for Rett syndrome phenotypes but essential for embryo viability and placenta development.
Masayuki Itoh,Candice G.T. Tahimic,Shuhei Ide,Akihiro Otsuki,Toshikuni Sasaoka,Shigeru Noguchi,Mitsuo Oshimura,Yu-ichi Goto,Akihiro Kurimasa +8 more
TL;DR: A novel role for MeCP2 in normal placenta development is suggested and how paternal X chromosome inactivation in extraembryonic tissues confers a survival disadvantage for carriers of a mutant maternal Me CP2_e2 allele is illustrated.
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Erratum: Inactivation of aPKCλ result in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex (Development vol. 133 (1735-1744))
Fumiyasu Imai,Syu Ichl Hirai,Kazunori Akimoto,Hiromichi Koyama,Takaki Miyata,Masaharu Ogawa,Shigeru Noguchi,Toshikuni Sasaoka,Tetsuo Noda,Ohno Shigeo +9 more
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PTB Deficiency Causes the Loss of Adherens Junctions in the Dorsal Telencephalon and Leads to Lethal Hydrocephalus
Takayuki Shibasaki,Akinori Tokunaga,Reiko Sakamoto,Hiroshi Sagara,Shigeru Noguchi,Toshikuni Sasaoka,Nobuaki Yoshida +6 more
TL;DR: It is demonstrated thatPTB depletion in the dorsal telencephalon is causally involved in the development of HC and that PTB is important for the maintenance of AJs in the NSCs of the dorsal Telencephalons.
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Effects of FAK ablation on cerebellar foliation, Bergmann glia positioning and climbing fiber territory on Purkinje cells
Fumihiro Watanabe,Taisuke Miyazaki,Tomonori Takeuchi,Masahiro Fukaya,Takanori Nomura,Shigeru Noguchi,Hisashi Mori,Kenji Sakimura,Masahiko Watanabe,Masayoshi Mishina +9 more
TL;DR: The results suggest that FAK in various neuronal and glial elements is required for the formation of normal histoarchitecture and cytoarchitectures in the cerebellum, and for the construction of proper innervation territory and synaptic wiring in PCs.
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