Shasha Bai
Nationwide Children's Hospital
10 Papers
13 Citations
Shasha Bai is an academic researcher from Nationwide Children's Hospital. The author has contributed to research in topics: Medicine & Gene. The author has an hindex of 1, co-authored 1 publications. Previous affiliations of Shasha Bai include Ohio State University.
Chat about Author
Papers
Sinisan alleviates depression-like behaviors by regulating mitochondrial function and synaptic plasticity in maternal separation rats.
Di Deng,Yongfei Cui,Shu Ying Gan,Zedan Xie,Sainan Cui,Kerun Cao,Shanshan Wang,Guoqi Shi,Lei Yang,Shasha Bai,Yafei Shi,Zhongqiu Liu,Jinlan Zhao,Rong Zhang +13 more
TL;DR: Wang et al. as mentioned in this paper investigated the role and precise mechanism of Sinisan on antidepressant of regulating mitochondrial function to improve hippocampal synaptic plasticity, which is the core of antidepressant prescription widely used in traditional Chinese medicine clinic treatment for depression induced by early life stress.
43
AAV1.NT-3 gene therapy for X-linked Charcot–Marie–Tooth neuropathy type 1
Burcak Ozes,Morgan Myers,Kyle Moss,Jennifer L. McKinney,Alicia Ridgley,Lei Chen,Shasha Bai,Shasha Bai,Charles K. Abrams,Mona M. Freidin,Jerry R. Mendell,Zarife Sahenk +11 more
TL;DR: In this paper, a CMTX-linked Charcot-Marie-Tooth neuropathy (CMTX) is caused by mutations in the gene encoding Gap Junction Protein Beta-1 (GJB1)/Connexin32 (Cx32) in Schwann cells.
Protective Effects of Resveratrol on Adolescent Social Isolation-Induced Anxiety-Like Behaviors via Modulating Nucleus Accumbens Spine Plasticity and Mitochondrial Function in Female Rats
Jinlan Zhao,Lihong Ye,Zuyi Liu,Yongfei Cui,Di Deng,Shasha Bai,Lei Yang,Yafei Shi,Zhongqiu Liu,Rong Zhang +9 more
TL;DR: Wang et al. as mentioned in this paper found that Resveratrol (RSV) is one of the most effective natural polyphenols with anti-anxiety and depression effects.
SiNiSan exerts antidepressant effects by modulating serotonergic/GABAergic neuron activity in the dorsal raphe nucleus region through NMDA receptor in the adolescent depression mouse model.
Kerun Cao,Jialong Zhong,Shanshan Wang,Yafei Shi,Shasha Bai,Jinlan Zhao,Lei Yang,Qi Liang,Di Deng,Rong Zhang +9 more
TL;DR: SiNiSan exhibits antidepressant effects in adolescent depression models by modulating serotonergic/GABAergic neuron activity in the dorsal raphe nucleus region through NMDA receptor downregulation, alleviating stress-induced depression in early life and adolescence.
3
The Effects of Early-Life Stress on Liver Transcriptomics and the Protective Role of EPA in a Mouse Model of Early-Life-Stress-Induced Adolescent Depression.
Lihong Ye,Jiayi Wu,Di Deng,Lin An,Shasha Bai,Lei Yang,Binjie Liu,Yafei Shi,Rong Zhang +8 more
TL;DR: ELS induces depression-like behavior in adolescent mice, altering the liver transcriptomics and decreasing EPA levels. EPA supplementation improves depression-like behavior.
3