Sharon Cassol
University of Pretoria
64 Papers
861 Citations
Sharon Cassol is an academic researcher from University of Pretoria. The author has contributed to research in topics: Viral load & Population. The author has an hindex of 32, co-authored 64 publications. Previous affiliations of Sharon Cassol include Medical Research Council & University of Ottawa.
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Papers
An automated genotyping system for analysis of HIV-1 and other microbial sequences
Tulio de Oliveira,Koen Deforche,Sharon Cassol,Mika Salminen,D Paraskevis,Christopher J. Seebregts,Joe Snoeck,Estrelita Janse van Rensburg,Annemarie M. J. Wensing,David A. M. C. van de Vijver,Charles A. Boucher,Ricardo Jorge Camacho,Anne-Mieke Vandamme +12 more
TL;DR: The development of an automated genotyping system that can be easily applied to HIV-1 and other rapidly evolving viral pathogens is described.
Persistent Microbial Translocation and Immune Activation in HIV-1-Infected South Africans Receiving Combination Antiretroviral Therapy
Edana Cassol,Susan Malfeld,Phetole Walter Mahasha,Schalk W. van der Merwe,Sharon Cassol,Christopher J. Seebregts,Massimo Alfano,Guido Poli,Theresa M. Rossouw +8 more
TL;DR: The relationship between markers of monocyte activation, plasma lipopolysaccharide (LPS), and HIV-1 RNA in South Africans prioritized to receive combination antiretroviral therapy (cART) suggests that their upregulation was driven by HIV- 1.
Mother-to-Child Transmission of Human Herpesvirus-8 in South Africa
Martin Dedicoat,Robert U. Newton,Khaled R. Alkharsah,Julie Sheldon,Ildiko Szabados,Bukekile Ndlovu,Taryn Page,Delphine Casabonne,Charles F. Gilks,Sharon Cassol,Denise Whitby,Thomas F. Schulz +11 more
TL;DR: Saliva could be a route of transmission of HHV-8 from person to person, although other routes cannot be ruled out.
Detection of HIV Type 1 env Subtypes A, B, C, and E in Asia Using Dried Blood Spots: A New Surveillance Tool for Molecular Epidemiology
Sharon Cassol,Bruce G. Weniger,P. G. Babu,Mika Salminen,X. Zheng,Myo Thet Htoon,A. Delaney,M. O'shaughnessy,C.-Y. Ou +8 more
TL;DR: The subtypes BB and E in Myanmar, and the BB in China, suggest epidemiological linkage with these subtypes in neighboring Thailand, and are a practical, economical technique for conducting large-scale molecular epidemiological surveillance to track the global distribution and spread of HIV-1 variants.
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Molecular characteristics of human immunodeficiency virus type 1 subtype C viruses from KwaZulu-Natal, South Africa: implications for vaccine and antiretroviral control strategies.
Michelle Gordon,T de Oliveira,Karen S. Bishop,Hoosen M. Coovadia,L. Madurai,Susan Engelbrecht,E. Janse van Rensburg,Anisa Mosam,A. Smith,Sharon Cassol +9 more
TL;DR: The KwaZulu-Natal region of South Africa is experiencing an explosive outbreak of human immunodeficiency virus type 1 (HIV-1) subtype C infections and the genetic diversity of C viruses and the biological consequences of this diversity are important for the design of effective control strategies.