Scott R. Burger
University of Minnesota
26 Papers
277 Citations
Scott R. Burger is an academic researcher from University of Minnesota. The author has contributed to research in topics: Transplantation & Bone marrow. The author has an hindex of 15, co-authored 25 publications. Previous affiliations of Scott R. Burger include University of Rochester.
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Papers
Potency assay development for cellular therapy products: an ISCT review of the requirements and experiences in the industry.
Christopher A. Bravery,Jessica Carmen,Timothy Fong,Wanda Oprea,Karin H. Hoogendoorn,Juliana Megan Woda,Scott R. Burger,Jon A. Rowley,Mark Bonyhadi,Wouter Van't Hof +9 more
TL;DR: The key observation and message is that aggressive early investment in a solid potency evaluation strategy can greatly enhance eventual CTP deployment because it can mitigate the risk of costly product failure in late-stage development.
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BCR/ABL-Negative Primitive Progenitors Suitable for Transplantation Can Be Selected From the Marrow of Most Early-Chronic Phase But Not Accelerated-Phase Chronic Myelogenous Leukemia Patients
Catherine M. Verfaillie,Ravi Bhatia,Ravi Bhatia,Wesley J. Miller,Wesley J. Miller,Frank Mortari,Frank Mortari,Vivek Roy,Vivek Roy,Scott R. Burger,Scott R. Burger,Jeff McCullough,Jeff McCullough,Kevin T. Stieglbauer,Kevin T. Stieglbauer,Gordon W. Dewald,Gordon W. Dewald,Shelly Heimfeld,Shelly Heimfeld,Jeffrey S. Miller,Jeffrey S. Miller,Philip B. McGlave,Philip B. McGlave +22 more
TL;DR: Large-scale selection of a BCR/ABL mRNA- and Ph-negative 34+DR- cell population is possible in a fraction of chronic-phase CML patients, in whom these cells could be used to reconstitute the hematopoietic compartment following autologous transplantation.
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Concise Review: Guidance in Developing Commercializable Autologous/Patient-Specific Cell Therapy Manufacturing
Shannon Eaker,Myriam Armant,Harvey Brandwein,Scott R. Burger,Andrew Campbell,Carmine Carpenito,Dominic M. Clarke,Timothy Fong,Ohad Karnieli,Knut Niss,Wouter Van't Hof,Ravenska Wagey +11 more
TL;DR: This technical review, members of the International Society for Cell Therapy provide guidance in developing commercializable autologous and patient‐specific manufacturing strategies from the perspective of process development.
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Patent
Infusible grade short-term cell storage medium for mononuclear cells
Scott R. Burger,Allison Hubel,John Jeffrey McCullough +2 more
- 21 Oct 1997
TL;DR: An infusible-grade storage medium that is capable of preserving the viability and function of stem cells, nucleated cells and other hematopoietic cells is provided in this paper.
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Clinical-scale selection of anti-CD3/CD28-activated T cells after transduction with a retroviral vector expressing herpes simplex virus thymidine kinase and truncated nerve growth factor receptor.
Paul J. Orchard,Bruce R. Blazar,Scott R. Burger,Bruce L. Levine,Lisa Basso,David Nelson,Keith Gordon,R. Scott McIvor,John E. Wagner,Jeffrey S. Miller +9 more
TL;DR: It is concluded that a strategy based on activation of human T cells with anti-CD3/CD28 beads can result in sufficient transduction, expansion, and purification based on NGFR expression for clinical trials.
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