Sarah Skinner
Claude Bernard University Lyon 1
37 Papers
42 Citations
Sarah Skinner is an academic researcher from Claude Bernard University Lyon 1. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 9, co-authored 27 publications. Previous affiliations of Sarah Skinner include University of North Carolina at Chapel Hill & University of Lyon.
Chat about Author
Papers
Blood Rheology: Key Parameters, Impact on Blood Flow, Role in Sickle Cell Disease and Effects of Exercise.
Elie Nader,Sarah Skinner,Marc Romana,Marc Romana,Romain Fort,Nathalie Lemonne,Nicolas Guillot,Alexandra Gauthier,Sophie Antoine-Jonville,Céline Renoux,Marie-Dominique Hardy-Dessources,Marie-Dominique Hardy-Dessources,Emeric Stauffer,Philippe Joly,Yves Bertrand,Philippe Connes +15 more
TL;DR: While acute, intense exercise may increase blood viscosity in healthy individuals, recent works conducted in sickle cell patients have shown that light cycling exercise did not cause dramatic changes in blood rheology, which could be beneficial for adequate blood flow and tissue perfusion.
Red blood cell microvesicles activate the contact system, leading to factor IX activation via 2 independent pathways.
Denis F. Noubouossie,Michael W. Henderson,Micah J. Mooberry,Anton Ilich,Patrick Ellsworth,Mark Piegore,Sarah Skinner,Rafal Pawlinski,Ian J. Welsby,Thomas Renné,Maureane Hoffman,Dougald M. Monroe,Nigel S. Key +12 more
TL;DR: Novel mechanisms by which RBC transfusion mediates inflammatory and/or thrombotic outcomes are suggested, namely the classical FXIIa-FXI-FIX pathway and via direct kallikrein activation of FIX.
73
Acute Cycling Exercise Induces Changes in Red Blood Cell Deformability and Membrane Lipid Remodeling.
Travis Nemkov,Sarah Skinner,Elie Nader,Davide Stefanoni,Mélanie Robert,Mélanie Robert,Francesca Cendali,Emeric Stauffer,Emeric Stauffer,Agnès Cibiel,Camille Boisson,Camille Boisson,Philippe Connes,Philippe Connes,Angelo D'Alessandro +14 more
TL;DR: In this article, the effects of a controlled, 30 min, high-intensity cycling test on blood rheology and metabolic profiles of red blood cells (RBCs) and plasma from well-trained males were described.
56
Association Between Nitric Oxide, Oxidative Stress, Eryptosis, Red Blood Cell Microparticles, and Vascular Function in Sickle Cell Anemia
Elie Nader,Marc Romana,Nicolas Guillot,Romain Fort,Emeric Stauffer,Emeric Stauffer,Nathalie Lemonne,Yohann Garnier,Yohann Garnier,Yohann Garnier,Sarah Skinner,Sarah Skinner,Maryse Etienne-Julan,Mélanie Robert,Alexandra Gauthier,Giovanna Cannas,Sophie Antoine-Jonville,Benoit Tressières,Marie-Dominique Hardy-Dessources,Marie-Dominique Hardy-Dessources,Marie-Dominique Hardy-Dessources,Yves Bertrand,Cyril Martin,Cyril Martin,Céline Renoux,Céline Renoux,Philippe Joly,Philippe Joly,Marijke Grau,Philippe Connes,Philippe Connes,Philippe Connes +31 more
TL;DR: The data show that oxidative stress could promote eryptosis and the release of RBC-MPs that are potentially involved in macrovascular dysfunction in SCA.
Does physical activity increase or decrease the risk of sickle cell disease complications
Cyril Martin,Cyril Martin,Vincent Pialoux,Vincent Pialoux,Vincent Pialoux,Camille Faes,Camille Faes,Emmanuelle Charrin,Emmanuelle Charrin,Sarah Skinner,Sarah Skinner,Philippe Connes,Philippe Connes,Philippe Connes +13 more
TL;DR: Reviewing the literature on the effects of acute and chronic exercise on the biological responses and clinical outcomes of patients with SCD shows that regular physical activity could decrease oxidative stress and inflammation, limit blood rheology alterations and increase nitric oxide metabolism.
43