Sang Eun Lee
University Health System
190 Papers
308 Citations
Sang Eun Lee is an academic researcher from University Health System. The author has contributed to research in topics: Medicine & Coronary artery disease. The author has an hindex of 27, co-authored 169 publications. Previous affiliations of Sang Eun Lee include Cedars-Sinai Medical Center & Ewha Womans University.
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Papers
Effects of Statins on Coronary Atherosclerotic Plaques: The PARADIGM Study
Sang Eun Lee,Hyuk Jae Chang,Ji Min Sung,Hyung Bok Park,Ran Heo,Asim Rizvi,Fay Y. Lin,Amit Kumar,Martin Hadamitzky,Yong Jin Kim,Edoardo Conte,Daniele Andreini,Gianluca Pontone,Matthew J. Budoff,Ilan Gottlieb,Byoung Kwon Lee,Eun Ju Chun,Filippo Cademartiri,Erica Maffei,Hugo Marques,Jonathon Leipsic,Sanghoon Shin,Jung Hyun Choi,Kavitha Chinnaiyan,Gilbert L. Raff,Renu Virmani,Habib Samady,Peter Stone,Daniel S. Berman,Jagat Narula,Leslee J. Shaw,Jeroen J. Bax,James K. Min +32 more
TL;DR: Statins were associated with slower progression of overall coronary atherosclerosis volume, with increased plaque calcification and reduction of high-risk plaque features, and induced phenotypic plaque transformation.
Coronary Atherosclerotic Precursors of Acute Coronary Syndromes
Hyuk Jae Chang,Fay Y. Lin,Sang Eun Lee,Daniele Andreini,Jeroen J. Bax,Filippo Cademartiri,Kavitha Chinnaiyan,Benjamin J.W. Chow,Edoardo Conte,Ricardo C. Cury,Gudrun Feuchtner,Martin Hadamitzky,Yong Jin Kim,Jonathon Leipsic,Erica Maffei,Hugo Marques,Fabian Plank,Gianluca Pontone,Gilbert L. Raff,Alexander R. van Rosendael,Todd C. Villines,Harald G. Weirich,Subhi J. Al'Aref,Lohendran Baskaran,Iksung Cho,Iksung Cho,Iksung Cho,Ibrahim Danad,Donghee Han,Donghee Han,Ran Heo,Ji Hyun Lee,Ji Hyun Lee,Asim Rivzi,Asim Rivzi,Wijnand J. Stuijfzand,Heidi Gransar,Yao Lu,Ji Min Sung,Hyung Bok Park,Daniel S. Berman,Matthew J. Budoff,Habib Samady,Leslee J. Shaw,Peter Stone,Renu Virmani,Jagat Narula,James K. Min +47 more
TL;DR: Although ACS increases with %DS, most precursors of ACS cases and culprit lesions are nonobstructive, and plaque evaluation, including HRP, PB, and plaque composition, identifies high-risk patients above and beyond stenosis severity and aggregate plaque burden.
396
Deep learning improves prediction of CRISPR–Cpf1 guide RNA activity
Hui Kwon Kim,Seonwoo Min,Myungjae Song,Myungjae Song,Soobin Jung,Jae Woo Choi,Younggwang Kim,Sang Eun Lee,Sungroh Yoon,Hyongbum Kim +9 more
TL;DR: Two algorithms to predict the activity of AsCpf1 guide RNAs are presented and it is shown that both algorithms outperform previous machine learning algorithms on their own and published data sets.
330
HMGB1 is phosphorylated by classical protein kinase C and is secreted by a calcium-dependent mechanism
TL;DR: It is proposed that cPKC is an effector kinase ofHMGB1 phosphorylation in LPS-stimulated monocytes and PI3K-phosphoinositide-dependent kinase 1 may act in concert to control HMGB1 secretion independent of the NF-κB, p38, and ERK pathways.
170
Peri-Coronary Adipose Tissue Density Is Associated With 18F-Sodium Fluoride Coronary Uptake in Stable Patients With High-Risk Plaques.
Jacek Kwiecinski,Damini Dey,Sebastien Cadet,Sang Eun Lee,Yuka Otaki,Phi T. Huynh,Mhairi K. Doris,Evann Eisenberg,Mijin Yun,Maurits A. Jansen,Michelle C. Williams,Balaji Tamarappoo,John D. Friedman,Marc R. Dweck,David E. Newby,Hyuk Jae Chang,Piotr J. Slomka,Daniel S. Berman +17 more
TL;DR: In patients with HRP features on coronary CTA, increased density of PCAT was associated with focal 18F-NaF PET uptake, and simultaneous assessment of these imaging biomarkers by 18f-Naf PET and CTA might refine cardiovascular risk prediction in stable patients withHRP features.
156