Ruiping He
Dalian Medical University
7 Papers
Ruiping He is an academic researcher from Dalian Medical University. The author has contributed to research in topics: Downregulation and upregulation & Chromatin immunoprecipitation. The author has an hindex of 7, co-authored 7 publications.
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Papers
LncRNAAC132217.4, a KLF8-regulated long non-coding RNA, facilitates oral squamous cell carcinoma metastasis by upregulating IGF2 expression
Xiaojie Li,Changhong Ma,Li Zhang,Na Li,Xiaohong Zhang,Jianya He,Ruiping He,Miaomiao Shao,Junling Wang,Lan Kang,Chuanchun Han +10 more
TL;DR: The identification of dysregulated intergenic lncRNAs in the highly metastatic OSCC cell line, UM-SCC6H, and it is demonstrated that the KLF8-AC132217.4-IGF2 signalling pathway plays a critical role in OSCC metastasis.
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Integrin-β5, a miR-185-targeted gene, promotes hepatocellular carcinoma tumorigenesis by regulating β-catenin stability.
Zhikun Lin,Ruiping He,Haifeng Luo,Chang Lu,Zhen Ning,Yuanhang Wu,Chuanchun Han,Guang Tan,Zhongyu Wang +8 more
TL;DR: The data reveal that the miR-185-ITGB5-β-catenin pathway plays an important role in HCC tumorigenesis, and ITGB5 may be a promising specific target for HCC therapy.
KLF4, a miR-32-5p targeted gene, promotes cisplatin-induced apoptosis by upregulating BIK expression in prostate cancer
Lu Zhang,Xiaojie Li,Yulin Chao,Ruiping He,Junqiang Liu,Yi Yuan,Wenzhi Zhao,Chuanchun Han,Xishuang Song +8 more
TL;DR: The data revealed that KLF4 is an essential regulator in cisplatin-induced apoptosis, and the miR-32-5p-KLF4-BIK signalling axis plays an important role in prostate cancer chemosensitivity.
Regulation of the adaptation to ER stress by KLF4 facilitates melanoma cell metastasis via upregulating NUCB2 expression.
Dongmei Zhang,Jingrong Lin,Yulin Chao,Lu Zhang,Lei Jin,Na Li,Ruiping He,Binbin Ma,Wenzhi Zhao,Chuanchun Han +9 more
TL;DR: KLF4 was induced by ER stress in melanoma cells, and increased KLF4 inhibited cell apoptosis and promoted cell metastasis, revealing that the promotion of ER stress resistance via the KLf4-NUCB2 axis is essential for melanomacell metastasis.
ZBTB7A, a miR-663a target gene, protects osteosarcoma from endoplasmic reticulum stress-induced apoptosis by suppressing LncRNA GAS5 expression.
TL;DR: The findings reveal the prosurvival role of ZBTB7A in osteosarcoma adaptation to ER stress and suggest that the miR-663a-ZBTB 7A-LncRNAGAS5 pathway is essential for the survival of human osteosARcoma cells under ER stress.