Ronald K. Siu
University of California, Los Angeles
17 Papers
59 Citations
Ronald K. Siu is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Bone regeneration & Bone morphogenetic protein. The author has an hindex of 16, co-authored 17 publications. Previous affiliations of Ronald K. Siu include University of California.
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Papers
The antimicrobial and osteoinductive properties of silver nanoparticle/poly (dl-lactic-co-glycolic acid)-coated stainless steel
Yi Liu,Zhong Zheng,Janette N. Zara,Ching Yun Hsu,Donnalisa E. Soofer,Kevin S. Lee,Ronald K. Siu,Lloyd S. Miller,Xinli Zhang,Doug Carpenter,Chunling Wang,Kang Ting,Chia Soo +12 more
TL;DR: It is found that SNPSA exhibited strong antibacterial activity in vitro and ex vivo, and promoted MC3T3-E1 pre-osteoblasts proliferation and maturation in vitro, and induced osteogenesis while suppressing bacterial survival in contaminated rat femoral canals.
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The use of BMP-2 coupled – Nanosilver-PLGA composite grafts to induce bone repair in grossly infected segmental defects
Zhong Zheng,Wei Yin,Wei Yin,Janette N. Zara,Weiming Li,Weiming Li,Jinny Kwak,Rachna Mamidi,Min Lee,Ronald K. Siu,Richard Ngo,Joyce Wang,Doug Carpenter,Xinli Zhang,Benjamin M. Wu,Kang Ting,Chia Soo +16 more
TL;DR: It is demonstrated that metallic nanosilver particles (with a size of 20-40nm)-poly(lactic-co-glycolic acid) (PLGA) composite grafts have strong antibacterial properties, making it an ideal antimicrobial for bone regeneration in infected wounds.
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Biomimetic apatite-coated alginate/chitosan microparticles as osteogenic protein carriers
TL;DR: Moldability can be achieved by mixing hyaluronan hydrogel with two types of particles: demineralized bone powder for osteoconductivity, and biomimetic apatite-coated alginate/chitosan microparticles for controlled Nell-1 delivery.
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Novel Wnt Regulator NEL-Like Molecule-1 Antagonizes Adipogenesis and Augments Osteogenesis Induced by Bone Morphogenetic Protein 2
Jia Shen,Aaron W. James,Xinli Zhang,Shen Pang,Janette N. Zara,Greg Asatrian,Michael F. Chiang,Min Lee,Kevork Khadarian,Alan Nguyen,Kevin S. Lee,Ronald K. Siu,Sotirios Tetradis,Kang Ting,Chia Soo +14 more
TL;DR: It is demonstrated that NELL-1 combined with BMP2 significantly optimizes osteogenesis in a rodent femoral segmental defect model by minimizing the formation of B MP2-induced adipose-filled cystlike bone.
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Effect of Nell-1 delivery on chondrocyte proliferation and cartilaginous extracellular matrix deposition.
TL;DR: The ability of Nell-1 to promote chondrocyte proliferation and deposition of cartilage-specific extracellular matrix materials is demonstrated and is demonstrated to be chondrogenic in a dose-dependent manner.
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