正しい方法がわかる臨床基本手技 : from the New England journal of medicine

Cigarette smoking impairs the therapeutic response to oral corticosteroids in chronic asthma

Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease that combines various clinical manifestations and pathophysiological mechanisms. It underlies the separation of patients with COPD by phenotypes, endotypes and a personalized therapy of this disease. The implementation of this approach is possible only with the use of appropriate biomarkers. One of the most important biomarkers of COPD is eosinophilia of blood and/or sputum, which is considered as a predictor of frequent exacerbations and the effectiveness of inhaled glucocorticosteroids in patients with COPD. The literature discusses the impact of eosinophilic inflammation on the prognosis, clinical and functional parameters in COPD, and the role of the targeted therapy in the treatment of eosinophilic COPD.

/pdf/eosinophilic-inflammation-in-chronic-obstructive-pulmonary-4mxy1mi0zu.pdf

Eosinophilic inflammation in chronic obstructive pulmonary disease

The annual European Respiratory Society (ERS) International Congress (held in Paris in 2018) was once again a platform for discussion of the highest-quality scientific research, cutting-edge techniques and innovative new therapies within the respiratory field. This article discusses only some of the high-quality research studies presented at this year's Congress, with a particular focus on airway diseases including asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis and cough, as presented through Assembly 5 of the ERS (Airway Diseases: Asthma and COPD). The authors establish the key take-home messages of these studies, compare their findings and place them in the context of current understanding.

https://openres.ersjournals.com/content/erjor/5/1/00225-2018.full.pdf

Research highlights from the 2018 European Respiratory Society International Congress: airway disease.

During the 2018 European Respiratory Society (ERS) International Congress in Paris the author of the best abstract from every assembly was awarded (based on the highest average score from the abstract reviewers for an author under 40 years of age). Best-abstract awardees were invited to write a short summary of their Congress experience and view on the evolving field of research of their respective assembly. The purpose of this article is to give the readers a fast overview of some of the Congress highlights and to give the stage to the young and promising best-abstract awardees, as they are the future of the ERS.

https://breathe.ersjournals.com/content/breathe/14/4/e137.full.pdf

ERS International Congress 2018: highlights from best-abstract awardees.

Blood eosinophil counts and treatment response in COPD: analyses of IMPACT

Blood eosinophils and treatment response with triple and dual combination therapy in COPD: analysis of the IMPACT trial

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Blood eosinophil counts and treatment response in COPD: analyses of IMPACT

Blood eosinophils and treatment response with triple and dual combination therapy in COPD: analysis of the IMPACT trial