10 Papers
247 Citations
Regat Seyoum is an academic researcher from Indiana University – Purdue University Indianapolis. The author has contributed to research in topics: Nucleus accumbens & GABAA receptor. The author has an hindex of 9, co-authored 10 publications.
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Papers
D1 dopamine receptor regulates alcohol‐motivated behaviors in the bed nucleus of the stria terminalis in alcohol‐preferring (P) rats
TL;DR: A salient role is suggested for the D1, but not the D2 and opioid receptors in selectively modulating EtOH‐motivated behaviors in the BST.
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The reinforcing properties of alcohol are mediated by GABA(A1) receptors in the ventral pallidum.
Harry L. June,Katrina L. Foster,Peter F. McKay,Regat Seyoum,James E. Woods,Scott C. Harvey,William J. A. Eiler,Collette Grey,Michelle R. Carroll,Shannan McCane,Cecily M. Jones,Wenyuan Yin,Dynesha Mason,Rancia Cummings,Marin Garcia,Chunrong Ma,P V V S Sarma,James M. Cook,Phil Skolnick +18 more
TL;DR: The present study indicates that βCCt is capable of antagonizing the reinforcing and the sedative properties of alcohol and may represent a prototype of a pharmacotherapeutic agent to effectively reduce alcohol drinking behavior in human alcoholics.
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GABA(A) and opioid receptors of the central nucleus of the amygdala selectively regulate ethanol-maintained behaviors.
Katrina L. Foster,Peter F. McKay,Regat Seyoum,Dana Milbourne,Wenyuan Yin,P V V S Sarma,James M. Cook,Harry L. June +7 more
TL;DR: The hypothesis that GABAA and opioid receptors within the CeA can selectively regulate EtOH-maintained responding is supported and may represent a novel target site in the development of prototypical GAB AA and opioidergic receptor ligands, which selectively reduce alcohol abuse in humans.
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The GABAA Receptor α1 Subtype in the Ventral Pallidum Regulates Alcohol-Seeking Behaviors
Scott C. Harvey,Katrina L. Foster,Pete F. McKay,Michelle R. Carroll,Regat Seyoum,James E. Woods,Collette Grey,Cecily M. Jones,Shannan McCane,Rancia Cummings,Dynesha Mason,Chunrong Ma,James M. Cook,Harry L. June +13 more
TL;DR: The selective suppression of 3-PBC on alcohol-maintained responding after central and parenteral administrations, together with its low-efficacy agonist profile, suggest that the reduction in alcohol- maintained behaviors was not attributable to a general suppression on consummatory behaviors.
Differential responding for brain stimulation reward and sucrose in high-alcohol-drinking (HAD) and low-alcohol-drinking (LAD) rats.
James E. Woods,Peter F. McKay,Jacob Masters,Regat Seyoum,Annabel Chen,Lorie La Duff,Michael J. Lewis,Harry L. June +7 more
TL;DR: In this article, the authors examined the associations among selective breeding for alcohol preference, intake of sweet solutions, and responding for brain stimulation reward (BSR), a nonoral reinforcer, in alcohol-preferring high-alcohol-drinking (HAD)-1 and non-preference low-alcohol drinking (LAD-1) rats.
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