Raphaël Boisgard
Université Paris-Saclay
75 Papers
789 Citations
Raphaël Boisgard is an academic researcher from Université Paris-Saclay. The author has contributed to research in topics: Translocator protein & In vivo. The author has an hindex of 27, co-authored 73 publications. Previous affiliations of Raphaël Boisgard include French Institute of Health and Medical Research & University of Paris-Sud.
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Papers
Enteric Delivery of Regenerating Family Member 3 alpha Alters the Intestinal Microbiota and Controls Inflammation in Mice With Colitis
Marion Darnaud,Marion Darnaud,Alexandre Dos Santos,Alexandre Dos Santos,Patrick Gonzalez,Patrick Gonzalez,Sandrine Augui,Sandrine Augui,Claire Lacoste,Claire Lacoste,Christophe Desterke,Gert De Hertogh,Emma Valentino,Emma Valentino,Emilie Braun,Emilie Braun,Jinzi Zheng,Raphaël Boisgard,Christel Neut,Laurent Dubuquoy,Franck Chiappini,Franck Chiappini,Didier Samuel,Didier Samuel,Patricia Lepage,Francesca Guerrieri,Joël Doré,Christian Bréchot,Christian Bréchot,Christian Bréchot,Nicolas Moniaux,Nicolas Moniaux,Jamila Faivre,Jamila Faivre +33 more
TL;DR: Mice with hepatocytes that express hREG3A, which travels to the intestinal lumen, are less sensitive to colitis than control mice, and h REG3A is found to alter the colonic microbiota by decreasing levels of ROS.
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Imaging Microglial/Macrophage Activation in Spinal Cords of Experimental Autoimmune Encephalomyelitis Rats by Positron Emission Tomography Using the Mitochondrial 18 kDa Translocator Protein Radioligand [18F]DPA-714
Galith Abourbeh,Benoit Thézé,Renaud Maroy,Albertine Dubois,Vincent Brulon,Yoann Fontyn,Frédéric Dollé,Bertrand Tavitian,Raphaël Boisgard +8 more
TL;DR: Using [18F]DPA-714, neuroinflammation in spinal cords of EAE-induced rats could be visualized by PET, offering a sensitive technique for monitoring neuroinflammatory lesions in the CNS and particularly in the spinal cord.
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Non-Invasive In Vivo Imaging of Calcium Signaling in Mice
Kelly L. Rogers,Sandrine Picaud,Emilie Roncali,Raphaël Boisgard,Cesare Colasante,Jacques Stinnakre,Bertrand Tavitian,Philippe Brulet +7 more
TL;DR: This non-invasive imaging technique opens new avenues for the analysis of Ca2+ signaling whenever whole body information in freely moving animals is desired, in particular during behavioral and developmental studies.
The translocator protein ligand [18F]DPA-714 images glioma and activated microglia in vivo
Alexandra Winkeler,Raphaël Boisgard,Ali R. Awde,Albertine Dubois,Benoit Thézé,Jinzi Zheng,Luisa Ciobanu,Frédéric Dollé,Thomas Viel,Andreas H. Jacobs,Bertrand Tavitian +10 more
TL;DR: The TSPO radioligand [18F]DPA-714 can be used for PET imaging of intracranial 9L glioma in different rat strains and the radiotracer showed high specificity for T SPO as demonstrated by the significant reduction of [18 fpa-714 binding in the tumour after administration of unlabelled DPA-712 or PK11195.
Reduced PBR/TSPO expression after minocycline treatment in a rat model of focal cerebral ischemia: a PET study using [(18)F]DPA-714.
TL;DR: A hallmark of the inflammatory reaction that follows focal cerebral ischemia is overexpression of the mitochondrial peripheral benzodiazepine receptor/18 kDa translocator protein (PBR/TSPO) in the monocytic lineage and astrocytes as discussed by the authors.
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