Philippe Reix
University of Lyon
138 Papers
506 Citations
Philippe Reix is an academic researcher from University of Lyon. The author has contributed to research in topics: Medicine & Cystic fibrosis. The author has an hindex of 23, co-authored 110 publications. Previous affiliations of Philippe Reix include Lyon College & Claude Bernard University Lyon 1.
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Papers
Efficacy and safety of lumacaftor and ivacaftor in patients aged 6-11 years with cystic fibrosis homozygous for F508del-CFTR: a randomised, placebo-controlled, phase 3 trial
Felix Ratjen,Christopher Hug,Gautham Marigowda,S. Tian,Xiaohong Huang,Sanja Stanojevic,Carlos E Milla,Paul Robinson,David Waltz,Jane C. Davies,Margaret Rosenfeld,Timothy D. Starner,George Z. Retsch-Bogart,James F. Chmiel,David M. Orenstein,Carlos Milla,Ronald C. Rubenstein,Seth Walker,Alexandra G Cornell,Fadi Asfour,Philip Black,John L. Colombo,Deborah Froh,Susanna A. McColley,Fadel Ruiz,Diana Quintero,Alicia Casey,Gary Mueller,Patrick A. Flume,Floyd Livingston,Michael J. Rock,Brian O'Sullivan,Howard Schmidt,Thomas Lahiri,John McNamara,Aaron Chidekel,Laura A. Sass,Thomas G. Keens,David Schaeffer,Melinda Solomon,Mark A. Chilvers,Larry C. Lands,Sibylle Junge,Matthias Griese,Doris Staab,Tacjana Pressler,Silke van Koningsburggen-Rietschel,Lutz Naehrlich,Alastair Reid,Ian M. Balfour-Lynn,Don S. Urquhart,Tim Lee,Anne Munck,Isabelle Sermet Gaudelus,Christiane De Boeck,Philippe Reix,Anne Malfroot,Stephanie Bui,Hiranjan Selvadurai,Philip Robinson,Claire E. Wainwright,Barry Clements,Jodi Hilton,Lena Hjelte +63 more
TL;DR: Patients, all site personnel including the investigator and the site monitor, and the study team were blinded, with the exception of site personnel needing this information in the event of medical emergency or pregnancy and patient safety and regulatory affairs personnel to meet serious adverse event reporting requirements.
293
New insights into pediatric idiopathic pulmonary hemosiderosis: the French RespiRare® cohort
Jessica Taytard,Nadia Nathan,Jacques de Blic,M. Fayon,Ralph Epaud,Antoine Deschildre,Françoise Troussier,Marc Lubrano,Raphaël Chiron,Philippe Reix,Pierrick Cros,Malika Mahloul,Delphine Michon,Annick Clement,Harriet Corvol +14 more
TL;DR: Analysis of potential contributors supports a role of auto-immunity in disease development and highlights the importance of genetic factors in pediatric IPH.
Characteristics of disorders associated with genetic mutations of surfactant protein C
Guillaume Thouvenin,Rola Abou Taam,Florence Flamein,Loïc Guillot,Muriel Le Bourgeois,Philippe Reix,M. Fayon,F. Counil,Ulrika Depontbriand,Delphine Feldmann,Hubert Ducou Le Pointe,Jacques de Blic,Annick Clement,Ralph Epaud +13 more
TL;DR: Although progressive improvement was seen in most patients, the development of new therapeutic strategies with minimal side effects is needed, as the definitive diagnosis requires genetic analysis.
110
New surfactant protein C gene mutations associated with diffuse lung disease
Loïc Guillot,Ralph Epaud,Guillaume Thouvenin,Laurence Jonard,A Mohsni,Rémy Couderc,F. Counil,J. de Blic,Rola Abou Taam,M. Le Bourgeois,Philippe Reix,Florence Flamein,Annick Clement,Delphine Feldmann +13 more
TL;DR: The results confirm that SFTPC mutations are a frequent cause of diffuse lung disease, and that I73T is the most frequent SFT PC mutation associated with diffuse Lung disease.
Combined pulmonary fibrosis and emphysema syndrome associated with familial SFTPC mutation
Vincent Cottin,Philippe Reix,Chahéra Khouatra,Françoise Thivolet-Béjui,Delphine Feldmann,Jean-François Cordier +5 more
TL;DR: High-resolution computed tomography of the chest showed conspicuous centrilobular emphysema in the upper zones of the lungs, and diffuse, infiltrative lung disease in the lower zones, even in areas devoid of infiltrative changes.
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