P. Lönnberg
University of Turku
12 Papers
373 Citations
P. Lönnberg is an academic researcher from University of Turku. The author has contributed to research in topics: Caudate nucleus & Putamen. The author has an hindex of 11, co-authored 12 publications.
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Papers
A postmortem study of brain nicotinic receptors in Parkinson's and Alzheimer's disease.
TL;DR: The present findings indicate that nicotinic receptors are affected not only in AD, but also in PD and that dysfunction of the cholinergic system in the frontal cortex is involved in the dementia process in PD.
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Age-dependent decline in human brain dopamine D1 and D2 receptors
TL;DR: The results show that the dopaminergic system degenerates in the aging striatum and may contribute to the frequent occurrence of extrapyramidal symptoms in the elderly.
204
Choline acetyltransferase activity and striatal dopamine receptors in Parkinson's disease in relation to cognitive impairment
TL;DR: It is shown that cognitive decline in PD is associated with reduced ChAT activity in the prefrontal cortex and the D1 dopamine receptor number in the caudate nucleus, even in the absence of AD-type pathology.
127
Brain muscarinic receptors in senile dementia
Juha O. Rinne,K. Laakso,P. Lönnberg,P. K. Mölsä,Leo Paljärvi,Jaakko Rinne,Erkki Säkö,Urpo K. Rinne +7 more
TL;DR: Changes in muscarinic receptor binding show that the cholinergic neurons in the limbic system are especially vulnerable in patients with AD and CD.
96
A post-mortem study on striatal dopamine receptors in Parkinson's disease.
TL;DR: There is a modest decline in the number of striatal dopamine D2 receptors in advanced patients with PD at the end stage of the disease, suggesting that intrinsic striatal cholinergic neurons are not affected in PD.
84