Nikola Tolić
Environmental Molecular Sciences Laboratory
61 Papers
586 Citations
Nikola Tolić is an academic researcher from Environmental Molecular Sciences Laboratory. The author has contributed to research in topics: Mass spectrometry & Proteome. The author has an hindex of 28, co-authored 55 publications. Previous affiliations of Nikola Tolić include University of Maryland, College Park & Pacific Northwest National Laboratory.
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Papers
High throughput proteome-wide precision measurements of protein expression using mass spectrometry
Ljiljana Paša-Tolić,Pamela K. Jensen,Gordon A. Anderson,Mary S. Lipton,Kim K. Peden,Suzana Martinović,Nikola Tolić,James E. Bruce,Richard D. Smith +8 more
TL;DR: The authors have developed an approach utilizing organisms cultured in stable-isotope labeled media to provide effective internal calibrants for all detected proteins, thus enabling precise proteome-wide measurement of changes in protein abundances resulting from cellular perturbations.
231
Advanced solvent based methods for molecular characterization of soil organic matter by high-resolution mass spectrometry.
Malak M. Tfaily,Rosalie K. Chu,Nikola Tolić,Kristyn M. Roscioli,Christopher R. Anderton,Ljiljana Paša-Tolić,Errol W. Robinson,Nancy J. Hess +7 more
TL;DR: The study of SOM molecules by ESI FTICR MS revealed new insight into the molecular-level complexity of organics contained in soils, and presented the first comparative study of the molecular composition of SOM from different ecosystems using ultra high-resolution mass spectrometry.
195
High-Throughput Proteomics Using High-Efficiency Multiple-Capillary Liquid Chromatography with On-Line High-Performance ESI FTICR Mass Spectrometry
Yufeng Shen,Nikola Tolić,Rui Zhao,Ljiljana Paša-Tolić,Lingjun Li,Scott J. Berger,Richard Harkewicz,Gordon A. Anderson,Mikhail E. Belov,Richard D. Smith +9 more
TL;DR: A high-efficiency multiple-capillary liquid chromatography (LC) system using commercial LC pumps was operated at a pressure of 10,000 psi to deliver mobile phases through a novel passive feedback valve arrangement that permitted mobile-phase flow path switching and efficient sample introduction.
175
Identification of Protein-Protein Interactions and Topologies in Living Cells with Chemical Cross-linking and Mass Spectrometry
Haizhen Zhang,Xiaoting Tang,Gerhard R. Munske,Nikola Tolić,Gordon A. Anderson,James E. Bruce +5 more
TL;DR: Initial studies resulted in identification of a set of protein-protein interactions and their contact/binding regions, suggesting that the PIR approach is particularly suited for studies of membrane protein- protein interactions, an area under-represented with current widely used approaches.
167
Informed-Proteomics: open-source software package for top-down proteomics
Jungkap Park,Paul D. Piehowski,Christopher S. Wilkins,Mowei Zhou,Joshua Mendoza,Grant M. Fujimoto,Bryson C. Gibbons,Jared B. Shaw,Yufeng Shen,Anil K. Shukla,Ronald J. Moore,Tao Liu,Vladislav A. Petyuk,Nikola Tolić,Ljiljana Paša-Tolić,Richard D. Smith,Samuel H. Payne,Sangtae Kim +17 more
TL;DR: Informed-Proteomics is presented, an open-source software suite for top-down proteomics analysis that consists of an LC-MS feature-finding algorithm, a database search algorithm, and an interactive results viewer that is compared with several other popular tools using human-in-mouse xenograft luminal and basal breast tumor samples.
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