Naoko Takeuchi
University of California, Los Angeles
14 Papers
152 Citations
Naoko Takeuchi is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Loss of heterozygosity & DNA methylation. The author has an hindex of 9, co-authored 14 publications.
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Papers
Methylation Analysis of Cell Cycle Control Genes in Adult T-Cell Leukemia/Lymphoma
TL;DR: The data indicate that inactivation of these cell cycle regulatory genes by hypermethylation is important in the development of ATL.
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Loss of H19 imprinting in adult T-cell leukaemia/lymphoma
Seisho Takeuchi,Wolf-Karsten Hofmann,Kunihiro Tsukasaki,Naoko Takeuchi,Takayuki Ikezoe,Masahide Matsushita,Yoshio Uehara,H. Phillip Koeffler +7 more
TL;DR: It is found that LOI of H19 is a frequent event in ATL, indicating that H19 may have an important role in transformation of many kinds of tumours.
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P53 codon 72 polymorphism is associated with disease progression in adult T-cell leukaemia/lymphoma.
Seisho Takeuchi,Masahide Matsushita,Kunihiro Tsukasaki,Naoko Takeuchi,Masao Tomonaga,Naoki Komatsu,Takayuki Ikezoe,Yoshio Uehara,H P Koeffler +8 more
TL;DR: The results suggest that the P53 polymorphism plays an important role in the progression of ATL, but a genetic polymorphism of the tumour necrosis factor gene enhanced susceptibility to ATL among HTLV-I carriers and polymorphisms at the methylenetetrahydrofolate reductase locus did not alter susceptibility.
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Tamoxifen-induced non-alcoholic steatohepatitis in patients with breast cancer: determination of a suitable biopsy site for diagnosis.
Yoriko Murata,Yasuhiro Ogawa,Toshiji Saibara,Akihito Nishioka,Naoko Takeuchi,Shinji Kariya,Saburo Onishi,Shoji Yoshida +7 more
TL;DR: The distribution of fatty infiltration in the liver is evaluated for determination of a suitable biopsy site for diagnosis of tamoxifen-induced non-alcoholic steatohepatitis (NASH) in patients with breast cancer to identify hepatic steatosis (HS).
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Allelotype analysis in relapsed childhood acute lymphoblastic leukemia.
Seisho Takeuchi,T Seriu,Jacques J.M. van Dongen,Tomasz Szczepański,Kunihiro Tsukasaki,Naoko Takeuchi,Anthony C Fermin,Hiromi Seo,Claus R. Bartram,H. Phillip Koeffler +9 more
TL;DR: Novel tumor-suppressor genes on chromosome arms 4q, 6q, and 17q, as well as the p16 and TEL genes, have an important role in the relapse of childhood ALL.
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