Mingxi Yu
Dalian University of Technology
6 Papers
Mingxi Yu is an academic researcher from Dalian University of Technology. The author has contributed to research in topics: Internal medicine & Phthalate. The author has an hindex of 5, co-authored 6 publications.
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Papers
Prenatal and neonatal exposure to perfluorooctane sulfonic acid results in changes in miRNA expression profiles and synapse associated proteins in developing rat brains.
TL;DR: The results indicated that miRNA had little direct regulatory effect on the expression of mRNAs and synapse-associated proteins tested in the developing rat brain exposed to PFOS, and it seems that the PFOS-induced synaptic dysfunctions and changes in transcripts resulted from a combinatory action of biological controllers and processes, rather than directed by one single factor.
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DEHP exposure in utero disturbs sex determination and is potentially linked with precocious puberty in female mice.
TL;DR: A possible association between in utero DEHP exposure and precocious puberty in the postnatal life of mice offspring is suggested, where disturbance of the sex determination regulating pathway acted as an important mechanism.
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Di (2-ethylhexyl) phthalate exposure during pregnancy disturbs temporal sex determination regulation in mice offspring
TL;DR: The results suggest that the potential mechanism of gonadal development disorder by DEHP may origin from repression of important male sex determination signaling pathway, involving Gadd45g → Gata4 → Sry → Sox9, and a better understanding of the association between phthalate esters exposure and the reductive disorder.
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Di(2-Ethylhexyl) Phthalate Exposure In Utero Damages Sertoli Cell Differentiation Via Disturbance of Sex Determination Pathway in Fetal and Postnatal Mice
TL;DR: The results suggest that in utero DEHP exposure damaged Sertoli cells in the postnatal life of mice offspring via disturbance of the differentiation regulating pathway, potentially inducing declines in spermatogenesis.
22
Effects of tamoxifen on autosomal genes regulating ovary maintenance in adult mice
TL;DR: The activation of a testis-specific molecular signaling cascade was a potentially important mechanism contributing to the gender disorder induced by TAM, which resulted in the differentiation of the ovaries to atestis-like phenotype in adult mice.