Milagros Rocha
University of Valencia
136 Papers
494 Citations
Milagros Rocha is an academic researcher from University of Valencia. The author has contributed to research in topics: Oxidative stress & Mitochondrion. The author has an hindex of 38, co-authored 126 publications. Previous affiliations of Milagros Rocha include Hospital Research Foundation & Complutense University of Madrid.
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Papers
Mitochondrial dynamics in type 2 diabetes: Pathophysiological implications
Susana Rovira-Llopis,Celia Bañuls,Noelia Diaz-Morales,Antonio Hernández-Mijares,Milagros Rocha,Victor M. Victor +5 more
TL;DR: The molecular pathways of mitochondria dynamics, their impairment under type 2 diabetes, and pharmaceutical approaches for targeting mitochondrial dynamics, such as mitochondrial division inhibitor-1 (mdivi-1), dynasore, P110 and 15-oxospiramilactone are discussed.
536
Relationship between Oxidative Stress, ER Stress, and Inflammation in Type 2 Diabetes: The Battle Continues
Estefanía Burgos-Morón,Zaida Abad-Jiménez,Aranzazu M. de Marañón,Francesca Iannantuoni,Irene Escribano-Lopez,Sandra López-Domènech,Christian Salom,Ana Jover,Vicente Mora,I Roldán,Eva Solá,Milagros Rocha,Victor M. Victor +12 more
TL;DR: The present review discusses the current knowledge of the relationship between oxidative stress, mitochondria, ER stress, inflammation, and lipotoxicity in T2D.
476
Oxidative stress, endothelial dysfunction and atherosclerosis.
Victor M. Victor,Milagros Rocha,Eva Solá,Celia Bañuls,Katherine García-Malpartida,Antonio Hernández Mijares +5 more
TL;DR: A summary of the cellular metabolism of reactive oxygen species (ROS) and its role in pathophysiological processes such as atherosclerosis; and currently available antioxidants and possible reasons for their efficacy and inefficacy in ameliorating oxidative stress-mediated diseases are provided.
268
Nanoparticles in Medicine: A Focus on Vascular Oxidative Stress.
María Dolores Mauricio,Solanye Guerra-Ojeda,Patricia Marchio,Soraya L. Valles,Martin Aldasoro,Irene Escribano-Lopez,José Raúl Herance,Milagros Rocha,Jose Mª Vila,Victor M. Victor +9 more
TL;DR: The types of nanoparticles according to their chemical composition and the general characteristics of their use in medicine are summarized and nanoparticles with antioxidant properties may improve vascular dysfunction associated with hypertension, diabetes mellitus, or atherosclerosis.
Role of free radicals in sepsis: antioxidant therapy.
TL;DR: The protective role of antioxidants against homeostatic disturbances such as those caused by endotoxin toxicity, their potential clinical use and the effects on the redox state of the immune cells is discussed.
166