Maya Frankfurt
Hofstra University
73 Papers
1.4K Citations
Maya Frankfurt is an academic researcher from Hofstra University. The author has contributed to research in topics: Dendritic spine & Hippocampus. The author has an hindex of 39, co-authored 70 publications. Previous affiliations of Maya Frankfurt include City University of New York & Touro College.
Chat about Author
Papers
Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood
TL;DR: It is demonstrated that gonadal steroids are necessary for the maintenance of normal adult CA1 hippocampal pyramidal cell structure and implies that CA1 pyramsidal cell dendritic spine density may fluctuate during the normal rat estrous cycle.
1.4K
Ovariectomized rats show decreased recognition memory and spine density in the hippocampus and prefrontal cortex.
TL;DR: The results suggest that cognitive impairments observed in OVX rats may be associated with morphological changes in brain areas mediating memory.
260
Gonadal Steroids Modify Dendritic Spine Density in Ventromedial Hypothalamic Neurons: A Golgi Study in the Adult Rat
TL;DR: When spine density of VMN neurons was assessed throughout the estrous cycle, it was determined that spine density was significantly lower at diestrus than proestrus, and there were no differences between intact male and female rats observed in any parameter.
251
Sexually Dimorphic Effects of Prenatal Stress on Cognition, Hormonal Responses, and Central Neurotransmitters
Rachel E. Bowman,Neil J. MacLusky,Yessenia Sarmiento,Maya Frankfurt,Marisa Gordon,Victoria N. Luine +5 more
TL;DR: Data reinforce the view that prenatal stress affects multiple aspects of brain development, interfering with the expression of normal behavioral, neuroendocrine, and neurochemical sex differences, and implications for the effects of prenatal stress on the development of sexually dimorphic endocrine and neurological disorders.
HMGB1 mediates cognitive impairment in sepsis survivors.
Sangeeta S. Chavan,Patricio T. Huerta,Sergio Robbiati,Sergio I. Valdés-Ferrer,Mahendar Ochani,Meghan Dancho,Maya Frankfurt,Bruce T. Volpe,Kevin J. Tracey,Betty Diamond +9 more
TL;DR: It is observed that serum levels of high mobility group box 1 (HMGB1), a critical mediator of acute sepsis pathophysiology, are increased and this indicates that elevated HMGB1 levels mediate cognitive decline in sepsi survivors, and it is suggested that it may be possible to prevent or reverse cognitive impairments in Sepsis survivors by administration of anti-HMGB 1 antibodies.