Mark E. Smith
United States Environmental Protection Agency
21 Papers
165 Citations
Mark E. Smith is an academic researcher from United States Environmental Protection Agency. The author has contributed to research in topics: Biology & Ceriodaphnia dubia. The author has an hindex of 12, co-authored 21 publications.
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Papers
Differential Gene Expression in Daphnia magna Suggests Distinct Modes of Action and Bioavailability for ZnO Nanoparticles and Zn Ions
Helen C. Poynton,James M. Lazorchak,Christopher A. Impellitteri,Mark E. Smith,Kim R. Rogers,Manomita Patra,Katherine A. Hammer,H. Joel Allen,Chris D. Vulpe +8 more
TL;DR: A specific pattern of differential expression of three biomarker genes including a multicystatin, ferritin, and C1q containing gene were confirmed and provide a suite of biomarkers for identifying environmental exposure to ZnO NPs and differentiating between NP and ionic exposure.
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A reformulated, reconstituted water for testing the freshwater amphipod, Hyalella azteca
TL;DR: RMHRW is the best candidate for a standard water for H. azteca testing because of the failure of MHRW and DMW to produce acceptable results, as well as the inability of other laboratories to produce LL/SQ.
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Assessing impacts of land-applied manure from concentrated animal feeding operations on fish populations and communities.
Jessica K. Leet,Linda S. Lee,Heather E. Gall,Reuben R. Goforth,Stephen A. Sassman,Denise A. Gordon,James M. Lazorchak,Mark E. Smith,Chad T. Jafvert,Maria S. Sepúlveda +9 more
TL;DR: Maximum observed hormone concentrations were well above the lowest observable effect concentrations for these hormones; however, complexities at the field scale make it difficult to directly relate hormone concentration and impacts on fish.
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Interlaboratory study of precision: Hyalella azteca and Chironomus tentans freshwater sediment toxicity assays
G. Allen Burton,Teresa J. Norberg-King,Duane A. Benoit,Gerald T. Ankley,P. V. Winger,Jody A. Kubitz,James M. Lazorchak,Mark E. Smith,Daniel J. Call,Christopher G. Ingersoll,Eugene Greer,F. James Dwyer,Kristin E. Day,Paul Kennedy,Margaret Stinson +14 more
TL;DR: Results showed standard 10-d whole-sediment toxicity test methods for the amphipod Hyalella azteca and the midge Chironomus tentans to have relatively low variance and acceptable levels of precision in interlaboratory comparisons.
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17α-ethynylestradiol-induced vitellogenin gene transcription quantified in livers of adult males, larvae, and gills of fathead minnows (Pimephales promelas)
David L. Lattier,Tirumuru V. Reddy,Denise A. Gordon,James M. Lazorchak,Mark E. Smith,Daniel E. Williams,Barry Wiechman,Robert W. Flick,Ann L. Miracle,Gregory P. Toth +9 more
TL;DR: Use of the model provides sensitivity of detection at a concentration below those that cause mortality or visible signs of stress in fish or other aquatic organisms, and may provide an in vivo screening method for estrogenlike endocrine‐disrupting compounds.
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