Mandar Paradkar
Johns Hopkins University
22 Papers
11 Citations
Mandar Paradkar is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Tuberculosis & Medicine. The author has an hindex of 7, co-authored 22 publications. Previous affiliations of Mandar Paradkar include Government Medical College, Thiruvananthapuram & Johns Hopkins University School of Medicine.
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Papers
Smoking, alcohol use disorder and tuberculosis treatment outcomes: A dual co-morbidity burden that cannot be ignored.
Beena E Thomas,Kannan Thiruvengadam,Sudha Rani,Dileep Kadam,Senthanro Ovung,Shrutha Sivakumar,Shri Vijay Bala Yogendra Shivakumar,Mandar Paradkar,Nikhil Gupte,Nishi Suryavanshi,Chandrakumar Dolla,Akshay Gupte,Rewa Kohli,Neeta Pradhan,Gomathi Sivaramakrishnan,Sanjay Gaikwad,Anju Kagal,Kavitha Dhanasekaran,Andrea DeLuca,Jonathan E. Golub,Vidya Mave,Padmapriyadarshini Chandrasekaran,Amita Gupta +22 more
TL;DR: Past and current smoking along with alcohol misuse have combined effects on increasing the risk of unfavourable TB treatment outcomes.
Tuberculosis preventive treatment should be considered for all household contacts of pulmonary tuberculosis patients in India
Mandar Paradkar,Chandrasekaran Padmapriyadarsini,Divyashri Jain,Shri Vijay Bala Yogendra Shivakumar,Kannan Thiruvengadam,Akshay Gupte,Beena E Thomas,Aarti Kinikar,Krithika Sekar,Renu Bharadwaj,Chandra Kumar Dolla,Sanjay Gaikwad,S. Elilarasi,Rahul Lokhande,Devarajulu Reddy,Lakshmi Murali,Vandana Kulkarni,Neeta Pradhan,Luke Elizabeth Hanna,Sathyamurthi Pattabiraman,Rewa Kohli,Sarita Rani,Nishi Suryavanshi,B M Shrinivasa,Samyra R. Cox,Sriram Selvaraju,Nikhil Gupte,Nikhil Gupte,Vidya Mave,Vidya Mave,Amita Gupta,Robert C. Bollinger +31 more
TL;DR: The findings support the new WHO recommendation to offer TPT to all HHC of PTB patients residing in a high TB burden country such as India, and do not suggest any benefit of TBI testing at baseline or during follow-up to risk stratify recently-exposed HHC for TPT.
Tuberculin skin test and QuantiFERON-Gold In Tube assay for diagnosis of latent TB infection among household contacts of pulmonary TB patients in high TB burden setting.
Padmapriyadarsini Chandrasekaran,Vidya Mave,Vidya Mave,Kannan Thiruvengadam,Nikhil Gupte,Nikhil Gupte,Shri Vijay Bala Yogendra Shivakumar,Luke Elizabeth Hanna,Vandana Kulkarni,Dileep Kadam,Kavitha Dhanasekaran,Mandar Paradkar,Beena E Thomas,Rewa Kohli,Chandrakumar Dolla,Renu Bharadwaj,Gomathi Sivaramakrishnan,Neeta Pradhan,Akshay Gupte,Lakshmi Murali,Chhaya Valvi,Soumya Swaminathan,Amita Gupta,Amita Gupta,CTRIUMPh RePORT India Study Team +24 more
TL;DR: Prevalence of LTBI among HHCs of adult pulmonary TB patients in India is very high and varies by test type, age, and exposure gradient, and a strategy to treat all H HCs or a targeted strategy whereby an exposure index is used should be assessed.
Infection free "resisters" among household contacts of adult pulmonary tuberculosis.
Vidya Mave,Padmapriyadarshini Chandrasekaran,Amol Chavan,Shri Vijay Bala Yogendra Shivakumar,Kavitha Danasekaran,Mandar Paradkar,Kannan Thiruvengadam,Aarti Kinikar,Lakshmi Murali,Sanjay Gaikwad,Luke Elizabeth Hanna,Vandana Kulkarni,Sathyamoorthy Pattabiraman,Nishi Suryavanshi,Beena E Thomas,Rewa Kohli,Gomathi Sivaramakrishnan,Neeta Pradhan,Brindha Bhanu,Anju Kagal,Jonathan E. Golub,Neel R. Gandhi,Akshay Gupte,Nikhil Gupte,Soumya Swaminathan,Amita Gupta +25 more
TL;DR: LTBI free resisters among HHC exist but are uncommon and are without distinguishing epidemiologic characteristics, likely to elucidate mechanisms of protective immunity to TB.
Age-specific prevalence of TB infection among household contacts of pulmonary TB: Is it time for TB preventive therapy?
Chandra Kumar Dolla,Chandrasekaran Padmapriyadarsini,Kannan Thiruvengadam,Rahul Lokhande,Aarti Kinikar,Mandar Paradkar,Shrinivas Bm,Lakshmi Murali,Akshay Gupte,Sanjay Gaikwad,Sriram Selvaraju,Yashoda Padmanaban,Sathyamurthy Pattabiraman,Neeta Pradhan,Vandana Kulkarni,Shri Vijay Bala Yogendra Shivakumar,Munivardhan Prithivi,Anju Kagal,Barath Thopili Karthavarayan,Nishi Suryavanshi,Nikhil Gupte,Paul Kumaran,Vidya Mave,Amita Gupta +23 more
TL;DR: An increased prevalence of LTBI and FI among older children and young adults recently exposed to infectious TB in the household is observed and expanding access to TB preventive therapy to all HHCs, including older children, may be beneficial to achieve TB elimination by 2035.
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