Lóránt Lakatos
University of Szeged
28 Papers
117 Citations
Lóránt Lakatos is an academic researcher from University of Szeged. The author has contributed to research in topics: RNA silencing & Trans-acting siRNA. The author has an hindex of 16, co-authored 26 publications. Previous affiliations of Lóránt Lakatos include French Institute of Health and Medical Research.
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Papers
Small RNA binding is a common strategy to suppress RNA silencing by several viral suppressors.
Lóránt Lakatos,Tibor Csorba,Vitantonio Pantaleo,Elisabeth J. Chapman,James C. Carrington,Yu Ping Liu,Valerian V. Dolja,Lourdes Fernández Calvino,Juan José López-Moya,József Burgyán +9 more
TL;DR: It is found that silencing suppressors p19, p21 and HC‐Pro each inhibit the intermediate step of RNA silencing via binding to siRNAs, although the molecular features required for duplex siRNA binding differ among the three proteins.
Low temperature inhibits RNA silencing-mediated defence by the control of siRNA generation
György Szittya,Dániel Silhavy,Attila Molnar,Zoltán Havelda,Agnes Lovas,Lóránt Lakatos,Zsófia Bánfalvi,József Burgyán +7 more
TL;DR: It is shown that in cold, plants become more susceptible to viruses, and RNA silencing‐based phenotypes of transgenic plants are lost, suggesting that the two classes of small RNAs are generated by different nuclease complexes.
Plant Virus-Derived Small Interfering RNAs Originate Predominantly from Highly Structured Single-Stranded Viral RNAs
TL;DR: The results suggest that virus-derived siRNAs originate predominantly by direct DICER cleavage of imperfect duplexes in the most folded regions of the positive strand of the viral RNA.
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Molecular mechanism of RNA silencing suppression mediated by p19 protein of tombusviruses
TL;DR: It is shown that p19 of Cymbidium ringspot virus (CymRSV) inhibits RNA silencing via its small RNA‐binding activity in vivo, and the obtained results suggest that the p19‐mediated sequestration of siRNAs in virus‐infected cells blocks the spread of the mobile, systemic signal of RNAsilencing.
Double-Stranded RNA Binding May Be a General Plant RNA Viral Strategy To Suppress RNA Silencing
TL;DR: Results show that many plant viral silencing suppressors bind dsRNAs, suggesting that dsRNA binding is a general silencing suppression strategy which has evolved independently many times.
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