Liting Jiang
Ningbo University
6 Papers
43 Citations
Liting Jiang is an academic researcher from Ningbo University. The author has contributed to research in topics: CpG site & DNA methylation. The author has an hindex of 6, co-authored 6 publications.
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Papers
Brilliant Blue G improves cognition in an animal model of Alzheimer's disease and inhibits amyloid-β-induced loss of filopodia and dendrite spines in hippocampal neurons.
Xiaowei Chen,Jun Hu,Liting Jiang,Shujun Xu,Bangxu Zheng,Chuang Wang,Junfang Zhang,Xiaofei Wei,Lan Chang,Qinwen Wang +9 more
TL;DR: It is reported that systematic administration of BBG diminishes spatial memory impairment and cognitive deficits in a mouse AD model produced by injecting soluble Aβ peptide into the hippocampal CA1 region, and it is shown that Aβ-induced loss of filopodia and spine density in cultured hippocampal neurons was prevented by administration ofBBG.
116
OPRK1 promoter hypermethylation increases the risk of Alzheimer's disease.
Huihui Ji,Yunliang Wang,Guili Liu,Xuting Xu,Dongjun Dai,Zhongming Chen,Dongsheng Zhou,Xiaohui Zhou,Liyuan Han,Ying Li,Renjie Zhuo,Qingxiao Hong,Liting Jiang,Xiaonan Zhang,Yu Liu,Lei Xu,Lan Chang,Jinfeng Li,Pengyuan An,Shiwei Duan,Qinwen Wang +20 more
TL;DR: The results suggested that O PRK1 promoter hypermethylation might increase the risk of AD through its regulation on the gene expression of OPRK1.
30
Bis(propyl)-cognitin Prevents β-amyloid-induced Memory Deficits as Well as Synaptic Formation and Plasticity Impairments via the Activation of PI3-K Pathway.
Liting Jiang,Meng Huang,Shujun Xu,Yu Wang,Pengyuan An,Chenxi Feng,Xiaowei Chen,Xiaofei Wei,Yifan Han,Qinwen Wang +9 more
TL;DR: It is found that the neuroprotective effect of B3C against Aβ-oligomer-induced impairments of synaptic formation and plasticity could be partially blocked by a specific phosphatidylinositol 3-kinase (PI3-K) inhibitor LY294002 (50 μM).
20
Population Difference in the Associations of KLOTH Promoter Methylation with Mild Cognitive Impairment in Xinjiang Uygur and Han Populations.
Mei Luo,Xiaohui Zhou,Huihui Ji,Wenjuan Ma,Guili Liu,Dongjun Dai,Jingyun Li,Lan Chang,Lei Xu,Liting Jiang,Shiwei Duan,Qinwen Wang +11 more
TL;DR: The results showed that KLOTHO promoter hypermethylation contributed to the MCI risk in Xinjiang Han Chinese but not in Beijing Uygur Chinese, and the population difference in the risk of MCI required further investigation in the future.
Elevated DRD4 promoter methylation increases the risk of Alzheimer's disease in males
Huihui Ji,Yunliang Wang,Danjie Jiang,Guili Liu,Xuting Xu,Dongjun Dai,Xiaohui Zhou,Wei Cui,Jinfeng Li,Zhongming Chen,Ying Li,Dongsheng Zhou,Qin Zha,Renjie Zhuo,Liting Jiang,Yu Liu,Lili Shen,Beibei Zhang,Lei Xu,Haochang Hu,Yuzheng Zhang,Honglei Yin,Shiwei Duan,Qinwen Wang +23 more
TL;DR: The results of the present study demonstrated that elevated DRD4 promoter methylation was associated with AD risk in males, and was significantly higher in AD patients than in controls.